| The relationship between serum thyrotropin and components of metabolic syndrome. | |
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MedLine Citation:
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PMID: 21135510 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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To explore the relationship between serum thyrotropin and components of metabolic syndrome in a Chinese cohort. A total of 1534 adult inhabitants in DaDong district of Shenyang were asked to fulfill the questionnaire, complete physical examination and OGTT. Blood samples were collected to test thyrotropin (TSH), fasting plasma glucose (FPG), OGTT 2h PG, fasting insulin (FINS), triglyceride (TG) and high density lipoprotein cholesterol (HDL-C). Serum TSH in metabolic syndrome group was higher than that in the non-metabolic syndrome group (2.54 mIU/L vs. 2.22 mIU/L, p<0.05). TG level increased significantly in subclinical hypothyroid group compared with euthyroid subjects (1.73±0.12 mmol/L vs. 1.47±0.03 mmol/L, p<0.05), and HDL-C decreased significantly in patients with subclinical hypothyroidism compared with euthyroid subjects (1.26±0.27 mmol/L vs. 1.33±0.27 mmol/L, p<0.05). The prevalence of hypertension was higher in the subclinical hypothyroid group than that in euthyroid group (42.86% vs. 33.2%, p<0.05). The serum TSH within the reference range was positively related with the prevalence of overweight/obesity. Slight increase in serum TSH maybe a risk factor for metabolic syndrome. |
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Authors:
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Yaxin Lai; Jiani Wang; Fengwei Jiang; Beibei Wang; Yanyan Chen; Mengchun Li; He Liu; Chenyan Li; Haibo Xue; Ningna Li; Jiashu Yu; Liangfeng Shi; Xue Bai; Xin Hou; Lin Zhu; Li Lu; Sen Wang; Qian Xing; Xiaochun Teng; Weiping Teng; Zhongyan Shan |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2010-11-30 |
Journal Detail:
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Title: Endocrine journal Volume: 58 ISSN: 1348-4540 ISO Abbreviation: Endocr. J. Publication Date: 2011 |
Date Detail:
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Created Date: 2011-02-04 Completed Date: 2011-05-16 Revised Date: 2011-06-16 |
Medline Journal Info:
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Nlm Unique ID: 9313485 Medline TA: Endocr J Country: Japan |
Other Details:
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Languages: eng Pagination: 23-30 Citation Subset: IM |
Affiliation:
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Department of Endocrinology and Metabolism, The First Hospital of China Medical University, No. 155 Nanjing Bei Street, Heping, Shenyang, China. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Aged, 80 and over Blood Glucose / metabolism China / epidemiology Cholesterol, HDL / blood Female Glucose Tolerance Test Humans Hypertension / epidemiology Hyperthyroidism / diagnosis Hypothyroidism / diagnosis Insulin / blood Male Metabolic Syndrome X / blood*, epidemiology Middle Aged Obesity / epidemiology Overweight Prevalence Thyrotropin / blood* Triglycerides / blood |
| Chemical | |
Reg. No./Substance:
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0/Blood Glucose; 0/Cholesterol, HDL; 0/Triglycerides; 11061-68-0/Insulin; 9002-71-5/Thyrotropin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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