Document Detail


The relationship between serum lipids and periodontitis in elderly non-smokers.
MedLine Citation:
PMID:  19405827     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: There are common risk factors for periodontal disease and cardiovascular disease in elderly patients. Some studies reported that a low total cholesterol (TC) serum level is associated with a higher level of death in the elderly. The purpose of this study was to investigate the relationship between serum lipids and periodontal disease in non-smoking elderly patients. METHODS: Two hundred thirty-four non-smokers (63 males and 171 females) participated in this study. Multiple regression analysis was performed to evaluate the relationship between serum lipids and periodontitis and between serum lipids and inflammatory factors. The percentage of sites with probing depth (PD) > or =4 mm, clinical attachment level (CAL) > or =4 mm, and bleeding on probing (BOP) were used as dependent variables. TC, high-density lipoprotein cholesterol (HDL-C), gender, and the number of teeth present were included in the model as independent variables in the first analysis. TC, HDL-C, and low-density lipoprotein cholesterol (LDL-C) were used as dependent variables. Albumin, inorganic phosphorus, calcium, and C-reactive protein were used as independent variables in the second analysis. RESULTS: According to the results of the multiple linear regression analysis, TC was associated with the percentage of sites with PD > or =4 mm (P <0.01; beta = -0.19), CAL > or =4 mm (P <0.01; beta = -0.20), and BOP (P = 0.03; beta = -0.16). HDL-C and LDL-C have a significant association with inflammatory markers and inorganic phosphorus and calcium, respectively. CONCLUSION: Higher TC is associated with a lower prevalence of periodontitis in non-smoking elderly patients.
Authors:
Aki Izumi; Akihiro Yoshihara; Toshinobu Hirotomi; Hideo Miyazaki
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of periodontology     Volume:  80     ISSN:  0022-3492     ISO Abbreviation:  J. Periodontol.     Publication Date:  2009 May 
Date Detail:
Created Date:  2009-05-01     Completed Date:  2009-08-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8000345     Medline TA:  J Periodontol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  740-8     Citation Subset:  D; IM    
Affiliation:
Division of Preventive Dentistry, Department of Oral Health Science, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan.
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MeSH Terms
Descriptor/Qualifier:
Aged
Cholesterol, HDL / blood
Cholesterol, LDL / blood
Chronic Periodontitis / blood*
Cross-Sectional Studies
Female
Humans
Linear Models
Lipids / blood*
Male
Smoking
Statistics, Nonparametric
Chemical
Reg. No./Substance:
0/Cholesterol, HDL; 0/Cholesterol, LDL; 0/Lipids

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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