| The relationship between self-monitoring of blood glucose results and glycated haemoglobin in type 2 diabetes: The Fremantle Diabetes Study. | |
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MedLine Citation:
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PMID: 21862165 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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The benefits of self-monitoring of blood glucose (SMBG) in type 2 diabetes remain contentious. If SMBG data do not accurately reflect HbA(1c), attempts to modify lifestyle/pharmacotherapy will be ineffective. We aimed to determine how well SMBG correlates with HbA(1c) and fasting serum glucose (FSG). Community-based type 2 patients using SMBG provided their highest and lowest pre- and post-prandial glucose results in the week before detailed assessment. The ability of average pre- and post-prandial SMBG to predict HbA(1c)>7.0% was determined by linear regression and receiver operating characteristic (ROC) analyses. Of 1286 patients with known SMBG status, 70% reported using SMBG. Pre-prandial SMBG data were obtained from 554 participants and post-prandial SMBG data from 418. The mean SMBG result and HbA(1c) correlated significantly (pre-prandial r(s)=0.55, post-prandial r(s)=0.47; P<0.001). Areas under the ROC curve (95% confidence limits) were 0.78 (0.74-0.83) and 0.74 (0.69-0.78) for pre- and post-prandial SMBG (P<0.04). The optimal cut-point was 6.5mmol/L for pre-prandial SMBG (sensitivity 79.3%, specificity 64.4%). Mean pre-prandial SMBG results correlated with FSG (r(s)=0.64, P<0.001) but were on average 1.4mmol/L lower, consistent with known whole blood vs. plasma differences. Since SMBG values reflect prevailing glycaemia, refinements in their interpretation and application may improve SMBG effectiveness. |
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Authors:
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S A Paul Chubb; Kylie Van Minnen; Wendy A Davis; David G Bruce; Timothy M E Davis |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-8-19 |
Journal Detail:
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Title: Diabetes research and clinical practice Volume: - ISSN: 1872-8227 ISO Abbreviation: - Publication Date: 2011 Aug |
Date Detail:
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Created Date: 2011-8-24 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8508335 Medline TA: Diabetes Res Clin Pract Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2011 Elsevier Ireland Ltd. All rights reserved. |
Affiliation:
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University of Western Australia, School of Pathology and Laboratory Medicine and Department of Biochemistry, PathWest Laboratory Medicine WA, Fremantle Hospital, Western Australia, Australia. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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