Document Detail

The relationship between placental histology and cervical length in twin gestations.
MedLine Citation:
PMID:  20443670     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To evaluate differences in placental lesions in twin pregnancies with and without mid-trimester sonographic cervical shortening.
METHODS: Two groups of women were identified: those with twin gestations and a cervical length <or=2.5 cm measured between 16 and 24 weeks of gestation and those with twin gestations and without evidence of cervical shortening. The placental pathology was then retrospectively reviewed. The placental lesions were categorized as either acute or chronic inflammatory lesions, lesions of malperfusion or coagulopathic lesions.
RESULTS: A total of 704 patients with twin gestations were identified. There was significantly more acute chorioamnionitis in patients with cervical shortening but no differences in the frequency of other placental lesions.
CONCLUSION: Placentas with acute inflammatory lesions are significantly more frequent in twin gestations with mid-trimester cervical shortening.
Linda M Peláez; Stephen T Chasen; Rebecca N Baergen
Publication Detail:
Type:  Journal Article; Twin Study    
Journal Detail:
Title:  Journal of perinatal medicine     Volume:  38     ISSN:  1619-3997     ISO Abbreviation:  J Perinat Med     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-09-03     Completed Date:  2011-01-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0361031     Medline TA:  J Perinat Med     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  485-9     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Weill Medical College of Cornell University, New York, NY 10065, USA.
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MeSH Terms
Cervical Length Measurement
Cervix Uteri / ultrasonography*
Chorioamnionitis / pathology,  ultrasonography
Cohort Studies
Gestational Age
Infant, Newborn
Placenta / pathology*,  ultrasonography*
Placenta Diseases / pathology,  ultrasonography
Pregnancy Trimester, First
Pregnancy Trimester, Second
Pregnancy, Multiple*
Premature Birth / etiology,  pathology,  ultrasonography
Retrospective Studies
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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