| The relationship between mixed venous and hepatic venous O2 saturation in patients with septic shock. | |
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MedLine Citation:
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PMID: 7915869 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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It was the purpose of this study to measure the relationship between hepatic venous O2 saturation (ShvO2) and mixed venous O2 saturation (SvO2) in septic patients (n = 21) following treatment with various catecholamines (epinephrine, norepinephrine, dopamine, dopexamine). At baseline mean SvO2 was 74 +/- 5% while mean ShvO2 was 59 +/- 12%. Alpha-mimetic substances such as epinephrine and norepinephrine reduced ShvO2 and increased the difference between SvO2 and ShvO2.Beta2-mimetic and dopaminergic substances (dopexamine, dopamine) did not change the difference between SvO2 and ShvO2. These results show that SvO2 does not necessarily reflect all changes of ShvO2. Monitoring ShvO2 may be helpful in managing septic shock by adding information on adequacy of O2 supply/consumption ratio in the crucial splanchnic region. |
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Authors:
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A Meier-Hellmann; L Hannemann; M Specht; W Schaffartzik; C Spies; K Reinhart |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Advances in experimental medicine and biology Volume: 345 ISSN: 0065-2598 ISO Abbreviation: Adv. Exp. Med. Biol. Publication Date: 1994 |
Date Detail:
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Created Date: 1994-10-06 Completed Date: 1994-10-06 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0121103 Medline TA: Adv Exp Med Biol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 701-7 Citation Subset: IM |
Affiliation:
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Department of Anesthesiology and Surgical Intensive Care Medicine, Steglitz Medical Center, Free University of Berlin, Germany. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Dobutamine
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pharmacology Dopamine / analogs & derivatives, pharmacology Dopamine Agents / pharmacology Epinephrine / pharmacology Hepatic Veins Humans Norepinephrine / pharmacology Oxygen / blood*, metabolism Oxygen Consumption / drug effects Shock, Septic / blood* Splanchnic Circulation / drug effects Veins |
| Chemical | |
Reg. No./Substance:
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0/Dopamine Agents; 34368-04-2/Dobutamine; 51-41-2/Norepinephrine; 51-43-4/Epinephrine; 7782-44-7/Oxygen; 86197-47-9/dopexamine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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