Document Detail

The relationship between maternal hematocrit and pregnancy outcome.
MedLine Citation:
PMID:  1988879     Owner:  NLM     Status:  MEDLINE    
The relationship between maternal hematocrit and pregnancy outcome at various times in pregnancy was studied in 17,149 iron- and folate-supplemented pregnant women. On univariate analysis, early-pregnancy hematocrits below 37% were associated with preterm delivery. However, this relationship was not confirmed by multivariate analysis controlling for other risk factors. On both univariate and multivariate analyses, both early and later in pregnancy, hematocrits above 40% were associated with preterm delivery. In every gestational time period, at least part of the excess of preterm births was explained by an increase in indicated preterm deliveries. In both early and late pregnancy, and in both the univariate and multivariate analyses, only high hematocrits were associated with fetal growth retardation. The strongest association (odds ratio above 2) between high hematocrit and both fetal growth retardation and preterm delivery occurred with hematocrits at or above 43% at 31-34 weeks' gestation.
Z M Lu; R L Goldenberg; S P Cliver; G Cutter; M Blankson
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  77     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  1991 Feb 
Date Detail:
Created Date:  1991-02-27     Completed Date:  1991-02-27     Revised Date:  2009-10-26    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  190-4     Citation Subset:  AIM; IM    
Department of Public Health Sciences, University of Alabama, Birmingham.
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MeSH Terms
Fetal Growth Retardation / blood*
Hematocrit / statistics & numerical data*
Obstetric Labor, Premature / blood*
Odds Ratio
Pregnancy Trimester, First
Pregnancy Trimester, Second
Pregnancy Trimester, Third
Comment In:
Obstet Gynecol. 1991 Jun;77(6):962-3   [PMID:  1867683 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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