| The relationship between estimated glomerular filtration rate and thyroid function: an observational study. | |
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MedLine Citation:
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PMID: 18753427 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Estimated glomerular filtration rate (eGFR) is now routinely reported by most National Health Service laboratories. There are many limitations when interpreting eGFR: thyroid dysfunction is not widely recognized as being one of these. METHODS: We extracted from the pathology computer system results of all patients with hypothyroidism and hyperthyroidism who also had serum creatinine measured. We also extracted creatinine data on euthyroid patients. eGFR was calculated using the simplified Modification of Diet in Renal Disease Study equation. RESULTS: The median eGFRs of the hypothyroid, euthyroid and hyperthyroid patients were 64, 77 and 107 mL/min/1.73 m(2), respectively; all groups were significantly different from each other (P < 0.001). CONCLUSION: Thyroid dysfunction is associated with significant alterations in eGFR and actual GFR. |
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Authors:
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Anne Woodward; Steven McCann; Mohammad Al-Jubouri |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Annals of clinical biochemistry Volume: 45 ISSN: 0004-5632 ISO Abbreviation: Ann. Clin. Biochem. Publication Date: 2008 Sep |
Date Detail:
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Created Date: 2008-08-28 Completed Date: 2008-11-13 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0324055 Medline TA: Ann Clin Biochem Country: England |
Other Details:
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Languages: eng Pagination: 515-7 Citation Subset: IM |
Affiliation:
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Department of Clinical Biochemistry, Whiston Hospital, Warrington Road, Merseyside, UK. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Aged, 80 and over Creatinine / blood Female Glomerular Filtration Rate* Humans Hyperthyroidism / blood Hypothyroidism / blood Kidney Diseases / blood Male Middle Aged Thyroid Function Tests / methods* Thyroid Gland / metabolism, pathology* |
| Chemical | |
Reg. No./Substance:
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60-27-5/Creatinine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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