Document Detail

The relationship between changes in the temporal and frequency characteristics of parasympathetic nerve activity and effects on the heart
MedLine Citation:
PMID:  1081458     Owner:  NLM     Status:  MEDLINE    
Changes of chronotropic effect on the frog heart on stimulation of part of extracardiac pathways, were studied. On the 10/sec stimulation during 1.5 sec, cardioinhibitory effect occurred. On 0.2 sec duration of the stimulation the positive chronotropic effect was observed. The heart rate increased on the 3/sec stimulation of the undegenerating extracardiac fibers by the 21st day after bilateral vagotomy; of the frequency of the stimulation was increased to 10/sec, the negative chronotropic effect occurred, and sympathectomy and the reserpine injection had no influence on the positive chrontropic effects. Both the negative and positive chronotropic effects could be prevented by atropine. The different chrontropic effects on the heart are, probably, due to activity of but a single functional type of fibers: the parasympathetic nervous fibers.
M G Udel'nov; G N Kopylova; N A Sokolova
Publication Detail:
Type:  English Abstract; Journal Article    
Journal Detail:
Title:  Fiziologicheskiĭ zhurnal SSSR imeni I. M. Sechenova     Volume:  61     ISSN:  0015-329X     ISO Abbreviation:  Fiziol Zh SSSR Im I M Sechenova     Publication Date:  1975 Nov 
Date Detail:
Created Date:  1976-03-01     Completed Date:  1976-03-01     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0427673     Medline TA:  Fiziol Zh SSSR Im I M Sechenova     Country:  USSR    
Other Details:
Languages:  rus     Pagination:  1664-9     Citation Subset:  IM    
Vernacular Title:
Zavisimost' éffektov na serdtse v zavisimosti ot izmenenii vremennykh i chastotnykh kharakteristik parasimpaticheskogo nervnogo vozdeĭstviia
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MeSH Terms
Electric Stimulation / methods
Heart / drug effects,  innervation*
Heart Rate
Parasympathetic Nervous System / physiology*
Rana temporaria
Reserpine / pharmacology
Time Factors
Reg. No./Substance:

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