| The relationship between central carbon dioxide sensitivity and clinical features in patients with chronic airways obstruction. | |
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MedLine Citation:
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PMID: 866574 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A technique has been developed which enables respiratory motor output to be measured independently of lung mechanics. The maximum rate of change of pressure at the mouth during initial transient occlusion of the airway, (d P/dt) max., represents the rate of isometric force development by the inspiratory muscles. This technique was used to study central CO2 sensitivity in 40 patients with chronic airways obstruction. Subnormal CO2 sensitivity was associated with chronic cough and sputum production, relatively mild dyspnoea, raised arterial CO2 tension, hypoxaemia, polycythaemia and cor pulmonale. Normal CO2 sensitivity was associated with severe dyspnoea, normal blood gas tensions, and allergic features. |
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Authors:
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A W Matthews |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Quarterly journal of medicine Volume: 46 ISSN: 0033-5622 ISO Abbreviation: Q. J. Med. Publication Date: 1977 Apr |
Date Detail:
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Created Date: 1977-07-29 Completed Date: 1977-07-29 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0401027 Medline TA: Q J Med Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 179-95 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Airway Obstruction / physiopathology* Carbon Dioxide* / blood Child Chronic Disease Dyspnea / physiopathology Female Humans Male Middle Aged Oxygen / blood Partial Pressure Pulmonary Emphysema / physiopathology |
| Chemical | |
Reg. No./Substance:
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124-38-9/Carbon Dioxide; 7782-44-7/Oxygen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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