Document Detail

The relationship between blood pressure and cognitive performance in the Third National Health and Nutrition Examination Survey (NHANES III).
MedLine Citation:
PMID:  15184686     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The present study examined the relationship between blood pressure and cognitive performance in 2727 healthy men and women between the ages of 20 and 59 years who participated in the Third National Health and Nutrition Examination Survey (NHANES III). METHODS: Participants were selected from a subsample of 5662 NHANES III respondents who completed an initial home interview, a medical examination, and a series of computerized cognitive tests of visuomotor reaction time, complex psychomotor speed (ie, symbol digit substitution), and verbal learning/attention (ie, serial digit learning). RESULTS: Hierarchical regressions tested the contribution of resting blood pressure to the prediction of performance on each of the cognitive tests. Results indicated that, after controlling for demographic variables (age, sex, race/ethnicity, education) and resting blood pressure, the interaction of systolic blood pressure by age was a significant predictor of performance on the test of verbal learning/attention. Follow-up analyses revealed that higher systolic blood pressure was associated with poorer performance in those younger than 40 years. CONCLUSIONS: Expanding on findings from previous epidemiological studies, the present study reports a small but significant relationship between resting blood pressure and cognitive performance that is particularly evident in younger healthy adults.
Julie A Suhr; Jesse C Stewart; Christopher R France
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Psychosomatic medicine     Volume:  66     ISSN:  1534-7796     ISO Abbreviation:  Psychosom Med     Publication Date:    2004 May-Jun
Date Detail:
Created Date:  2004-06-08     Completed Date:  2004-07-19     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0376505     Medline TA:  Psychosom Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  291-7     Citation Subset:  IM    
Department of Psychology, Ohio University, Athens, OH 45701, USA.
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MeSH Terms
Age Factors
Attention / physiology
Blood Pressure / physiology*
Blood Pressure Determination
Cognition / physiology*
Cognition Disorders / diagnosis,  epidemiology
Health Surveys
Hypertension / diagnosis,  epidemiology
Learning / physiology
Middle Aged
Neuropsychological Tests*
Nutrition Surveys
Psychomotor Performance / physiology
Reaction Time / physiology
United States / epidemiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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