| The relationship between asymptomatic human immunodeficiency virus infection and the prevalence and severity of anemia in pregnant Malawian women. | |
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MedLine Citation:
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PMID: 9886214 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The relationship between asymptomatic human immunodeficiency virus (HIV) infection and blood hemoglobin (Hb) concentration was examined in anemic pregnant women from a population with high prevalence of both anemia (60%) and HIV seropositivity (30%). Sera from 155 pregnant women with Hb levels < 10.5 g/dL were tested for HIV status, C-reactive protein (CRP), vitamin B12, retinol, and folate levels. The observed prevalence of HIV seropositivity in the group of women with anemia was 47.1% (95% confidence interval=39.2-55.0%). This is significantly higher than the HIV prevalence in the whole population (30.1%; P < 0.001). Median Hb values in HIV-seropositive and -seronegative women with anemia were 8.40 g/dL and 8.95 g/dL, respectively. Serum retinol, vitamin B12, and folate levels were not significantly different in the HIV-seropositive and -seronegative groups. In women who were HIV-seropositive with normal levels of CRP, a median decrease in Hb of 0.4 g/dL was observed. For those with serum CRP levels > 25 mg/l, the median decrease in Hb was 0.7 g/dL. Results indicate that asymptomatic HIV infection is associated with increased prevalence and severity of anemia in pregnancy in this population. |
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Authors:
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N R van den Broek; S A White; J P Neilson |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The American journal of tropical medicine and hygiene Volume: 59 ISSN: 0002-9637 ISO Abbreviation: Am. J. Trop. Med. Hyg. Publication Date: 1998 Dec |
Date Detail:
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Created Date: 1999-01-21 Completed Date: 1999-01-21 Revised Date: 2010-08-25 |
Medline Journal Info:
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Nlm Unique ID: 0370507 Medline TA: Am J Trop Med Hyg Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1004-7 Citation Subset: AIM; IM; X |
Affiliation:
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Department of Obstetrics and Gynaecology, University of Malawi, College of Medicine, Blantyre. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anemia
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epidemiology*,
etiology Cross-Sectional Studies Erythropoiesis Female HIV Infections / blood* Hemoglobins / analysis Humans Pregnancy Pregnancy Complications, Infectious / blood* Prevalence |
| Grant Support | |
ID/Acronym/Agency:
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//Wellcome Trust |
| Chemical | |
Reg. No./Substance:
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0/Hemoglobins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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