Document Detail

The relationship between alcohol consumption during pregnancy and infant birthweight. An epidemiologic study.
MedLine Citation:
PMID:  1746254     Owner:  NLM     Status:  MEDLINE    
Heavy alcohol consumption during pregnancy has been consistently associated with inhibited intra-uterine growth; however, the effect of social drinking is not yet clear. The relationship between moderate drinking and low birth weight (less than 2,500 g) among a nationally representative sample of white married mothers who gave birth to singletons infants in the National Natality Survey (1980) is analysed here. Alcohol consumption during pregnancy was significantly associated with birth weight (p less than 0.02). Moreover, there was a gradient of risk in low birth weight associated with increasing amount of alcohol ingestion during pregnancy. There was a significant association between the mean birth weight of the singletons across different categories of alcohol intake (p less than 0.0001). The difference between the mean birth weight of the singletons among moderate drinkers compared with nondrinkers was also statistically significant (p less than 0.005). These relationships remained after simultaneously adjusting effects of the confounding variables gestational age, parity, smoking, weight gain, maternal age and education in multiple regression analyses. These findings confirm earlier reports of a relationship between alcohol use during pregnancy and decreased birth weight. Additionally, it is shown here that for moderate alcohol use during pregnancy, there is an adverse effect on the birth weight.
S K Virji
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Acta obstetricia et gynecologica Scandinavica     Volume:  70     ISSN:  0001-6349     ISO Abbreviation:  Acta Obstet Gynecol Scand     Publication Date:  1991  
Date Detail:
Created Date:  1992-01-16     Completed Date:  1992-01-16     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0370343     Medline TA:  Acta Obstet Gynecol Scand     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  303-8     Citation Subset:  IM    
Center for Environmental Epidemiology, University of Pittsburgh, Pennsylvania.
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MeSH Terms
Alcohol Drinking / adverse effects*
Birth Weight / drug effects*
Gestational Age
Infant, Low Birth Weight
Infant, Newborn
Maternal Age
Smoking / adverse effects
Weight Gain
Grant Support
87MO12477501D//PHS HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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