Document Detail

The relationship of the baseline ECG to blood pressure change.
MedLine Citation:
PMID:  6224026     Owner:  NLM     Status:  MEDLINE    
A total of 1,090 male participants (aged 23 to 80 years) of the Normative Aging Study who had baseline BP less than 140/90 mm Hg were observed prospectively for ten years. Blood pressures were taken at five- and ten-year follow-up examinations. Multiple linear regression analysis indicated that baseline levels of systolic pressure, age, R-wave amplitude (aVL), hematocrit, T-wave amplitude (V5), and S-wave amplitude (V4, V5, and V6) were statistically significant predictors of systolic pressure change. Baseline levels of diastolic pressure, R-wave amplitude (aVL), and hematocrit were statistically significant predictors of diastolic pressure change. Multiple logistic regression analysis showed that baseline levels of BP, S-wave amplitude (V1, V2, and V3), body mass index, R-wave amplitude (V4, V5, and V6), and T-wave amplitude (V5) were statistically significant predictors of subsequent hypertension. Whether the identified ECG amplitudes are an indicator of early increases in peripheral resistance or a function of neurohumoral factors, or both, is unknown.
D Sparrow; H E Thomas; B Rosner; S T Weiss
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  JAMA     Volume:  250     ISSN:  0098-7484     ISO Abbreviation:  JAMA     Publication Date:  1983 Sep 
Date Detail:
Created Date:  1983-09-23     Completed Date:  1983-09-23     Revised Date:  2014-09-17    
Medline Journal Info:
Nlm Unique ID:  7501160     Medline TA:  JAMA     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1285-8     Citation Subset:  AIM; IM    
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MeSH Terms
Age Factors
Blood Pressure*
Cardiomegaly / physiopathology
Hypertension / etiology,  physiopathology
Middle Aged
Prospective Studies

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