Document Detail


The relationship of a 6-min walk to VO(2 peak) and VT in older heart failure patients.
MedLine Citation:
PMID:  16775543     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To evaluate the relationship between a 6-min walk test (6-MWT) to peak oxygen consumption (VO(2 peak)) and ventilatory threshold (VT) in older heart failure (HF) patients, to validate the equation by Cahalin et al., and to develop a new equation to improve the prediction of VO(2 peak) from 6-MWT.
METHODS: Older patients (>65 yr) with systolic or diastolic HF (N=97) performed an exercise test to peak exertion on an upright bicycle ergometer using an incremental protocol. Gas exchange measures were collected along with continuous electrocardiograph monitoring. 6-MWT was performed on an indoor track at a self-selected pace under standardized conditions. The formula of Cahalin et al. was used to predict VO(2 peak) from 6-MWT, and a new equation was generated from the measured VO(2 peak)-6-MWT relationship from this investigation.
RESULTS: The correlation between 6-MWT and measured VO(2 peak) was moderate (r=0.54) with a standard error of estimate (SEE) of 2.48 mL.kg.min. The correlation between 6-MWT and VT was weak (r=0.23), whereas the correlation between VO(2 peak) and VT was strong (r=0.74). Correlations between the measured and predicted VO(2 peak) values were moderate (r=0.54) for both prediction equations, and the SEE was 2.83 versus 1.34 mL.kg.min for the Cahalin et al. and the new equation, respectively.
CONCLUSION: These results indicate that 6-MWT does not accurately predict functional capacity in older HF patients, and questions the validity of using this test to determine functional capacity in older HF patients. Predicting VO(2 peak) from equations using 6-MWT also results in substantial variability and, consequently, should not be used in older HF patients where an accurate determination of functional capacity is essential.
Authors:
Sara Maldonado-Martín; Peter H Brubaker; Leonard A Kaminsky; J Brian Moore; Kathryn P Stewart; Dalane W Kitzman
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural    
Journal Detail:
Title:  Medicine and science in sports and exercise     Volume:  38     ISSN:  0195-9131     ISO Abbreviation:  Med Sci Sports Exerc     Publication Date:  2006 Jun 
Date Detail:
Created Date:  2006-06-15     Completed Date:  2006-10-27     Revised Date:  2012-05-17    
Medline Journal Info:
Nlm Unique ID:  8005433     Medline TA:  Med Sci Sports Exerc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1047-53     Citation Subset:  IM; S    
Affiliation:
Faculty of Physical Activity and Sport Sciences, University of Basque Country, Vitoria-Gasteiz, Araba, Basque Country, SPAIN.
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MeSH Terms
Descriptor/Qualifier:
Aged
Anaerobic Threshold / physiology*
Blood Pressure / physiology
Carbon Dioxide / analysis
Cardiac Output, Low / metabolism,  physiopathology*
Cohort Studies
Electrocardiography
Exercise Test
Exercise Tolerance / physiology
Female
Forecasting
Heart Rate / physiology
Humans
Male
Models, Biological
Oxygen Consumption / physiology*
Reproducibility of Results
Spirometry
Time Factors
Walking / physiology*
Grant Support
ID/Acronym/Agency:
AG12257/AG/NIA NIH HHS; AG18915/AG/NIA NIH HHS; M01RR07122/RR/NCRR NIH HHS; P60AG10484/AG/NIA NIH HHS; R37 AG018915/AG/NIA NIH HHS
Chemical
Reg. No./Substance:
124-38-9/Carbon Dioxide
Comments/Corrections
Comment In:
Med Sci Sports Exerc. 2007 Feb;39(2):391; author reply 392   [PMID:  17277605 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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