Document Detail

The relation between the estimated dietary intake of PCDD/Fs and levels in blood in a Flemish population (50-65 years).
MedLine Citation:
PMID:  18602159     Owner:  NLM     Status:  MEDLINE    
Dioxin-like activity was measured in the serum of 1425 Flemish men and women via the CALUX assay. The adults, aged between 50 and 65 years, participated in a large biomonitoring program, executed by the Flemish Center of Expertise for Environment and Health between 2002 and 2006. Within the context of this biomonitoring program also dietary intake of dioxin-like contaminants was assessed through a food frequency questionnaire. The relation between the estimated dietary intake and the dioxin-like activity in serum was evaluated using multivariate analyses: a logistic model was performed on the total population, while a linear regression analysis was done on the subsample with quantifiable dioxin activity levels in serum. Region, gender, age, BMI, smoking status, as well as dietary habits were entered in the model, with dioxin level as an outcome estimate. Both the logistic and linear model confirmed the contribution of dietary intake to the dioxin activity measured in serum. Also BMI and region were found to be associated with dioxin activity levels.
Maaike Bilau; Stefaan De Henauw; Carmen Schroijen; Liesbeth Bruckers; Elly Den Hond; Gudrun Koppen; Christophe Matthys; Els Van De Mieroop; Hans Keune; Willy Baeyens; Vera Nelen; Nik Van Larebeke; Jan L Willems; Greet Schoeters
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2008-07-03
Journal Detail:
Title:  Environment international     Volume:  35     ISSN:  1873-6750     ISO Abbreviation:  Environ Int     Publication Date:  2009 Jan 
Date Detail:
Created Date:  2008-12-08     Completed Date:  2009-02-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7807270     Medline TA:  Environ Int     Country:  United States    
Other Details:
Languages:  eng     Pagination:  9-13     Citation Subset:  IM    
Department of Public Health, Ghent University, UZ 2 Blok A, De Pintelaan 185, B-9000 Ghent, Belgium.
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MeSH Terms
Blood Chemical Analysis*
Middle Aged
Multivariate Analysis
Risk Factors
Tetrachlorodibenzodioxin / analogs & derivatives*,  blood,  metabolism
Reg. No./Substance:
0/polychlorodibenzo-4-dioxin; 1746-01-6/Tetrachlorodibenzodioxin

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