| A relation between childhood sun exposure and dysplastic nevus syndrome among patients with nonfamilial melanoma. | |
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MedLine Citation:
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PMID: 2054404 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We studied 117 patients with nonfamilial melanoma to determine whether melanoma patients with dysplastic nevus syndrome might be distinguished, on the basis of solar exposure, from melanoma patients without dysplastic nevus syndrome. Study participants were interviewed and received a skin examination, which included a total count of nevi, a standardized assessment of clinically atypical nevi, and the excision of each patient's clinically most atypical nevus. Based on the histologic review of the clinically most atypical nevus, each patient was classified as to whether dysplastic nevus syndrome was present or absent. Childhood sunburn with blistering and childhood recreational sun exposure were found to be associated with dysplastic nevus syndrome. The results suggest that childhood sun exposure increases risk of melanoma by initiating the melanoma precursor syndrome. |
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Authors:
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L Titus-Ernstoff; M S Ernstoff; P H Duray; R L Barnhill; R Holubkov; J M Kirkwood |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Epidemiology (Cambridge, Mass.) Volume: 2 ISSN: 1044-3983 ISO Abbreviation: Epidemiology Publication Date: 1991 May |
Date Detail:
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Created Date: 1991-08-01 Completed Date: 1991-08-01 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 9009644 Medline TA: Epidemiology Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 210-4 Citation Subset: IM |
Affiliation:
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Department of Epidemiology, Yale University School of Medicine, New Haven, CT 06510. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Age Factors Aged Connecticut / epidemiology Dysplastic Nevus Syndrome / epidemiology, etiology* Environmental Exposure Female Humans Male Melanoma / epidemiology, etiology* Middle Aged Risk Factors Skin Neoplasms / epidemiology, etiology* Social Class Sunlight / adverse effects* |
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