Document Detail


The relation between Chlamydia pneumoniae infection and abdominal aortic aneurysm: case-control study.
MedLine Citation:
PMID:  10880309     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Due to recent interest in the role of Chlamydia pneumoniae as a pathogen of the vascular system, a case-control study was conducted to investigate the association between serological evidence of infection with C. pneumoniae and the occurrence of abdominal aortic aneurysm. Detectable IgG antibody to C. pneumoniae was more common among abdominal aortic aneurysm cases than among control patients (adjusted odds ratio, 5.97; P = .08), as was detectable IgM antibody (10% vs. 0%; P = .02). These findings suggest that infection with C. pneumoniae may play a role in the pathogenesis of abdominal aortic aneurysm; therefore, further research in this area is warranted.
Authors:
J F Blanchard; H K Armenian; R Peeling; P P Friesen; C Shen; R C Brunham
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America     Volume:  30     ISSN:  1058-4838     ISO Abbreviation:  Clin. Infect. Dis.     Publication Date:  2000 Jun 
Date Detail:
Created Date:  2000-09-12     Completed Date:  2000-09-12     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9203213     Medline TA:  Clin Infect Dis     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  946-7     Citation Subset:  IM    
Affiliation:
Departments of Community Health Sciences and Medical Microbiology, Faculty of Medicine, University of Manitoba, Winnipeg, Manitoba R3E 0W3, Canada. blancha0@cc.umanitoba.ca
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MeSH Terms
Descriptor/Qualifier:
Antibodies, Bacterial / blood
Aortic Aneurysm, Abdominal / microbiology*
Case-Control Studies
Chlamydia Infections / complications*,  microbiology
Chlamydophila pneumoniae* / immunology
Humans
Chemical
Reg. No./Substance:
0/Antibodies, Bacterial

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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