| The relation of Graves' ophthalmopathy to circulating thyroid hormone status. | |
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MedLine Citation:
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PMID: 14693778 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIM: The risk factors and epidemiological data for Graves' ophthalmopathy with and without abnormal circulating thyroid levels were examined to determine the relation of thyroid dysfunction to ophthalmopathy. METHODS: The authors retrospectively evaluated 482 patients seen with Graves' ophthalmopathy. Of these, 413 were classified as having abnormal levels of circulating thyroid hormone (ALTH) and 69 as having normal levels of circulating thyroid hormone (NLTH). RESULTS: Patients in the NLTH group, compared to the ALTH group, were older on average (56 (SD 13.5) v 52 (15.4)) and had a higher age adjusted body mass index (26.1 (0.8) v 23.4 (0.3)). In addition, a higher percentage of NLTH patients had hypercholesterolaemia. Those in the ALTH group were more likely to be female (76% v 51%), to have a family history of thyroid problems, and to have had eye surgery. CONCLUSION: NLTH and ALTH appear to differ from each other in terms of risk factors and epidemiological characteristics. Additionally, thyroid dysfunction seems to be associated with a more severe ophthalmopathy compared to the euthyroid state. |
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Authors:
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J M Kim; L LaBree; L Levin; S E Feldon |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: The British journal of ophthalmology Volume: 88 ISSN: 0007-1161 ISO Abbreviation: Br J Ophthalmol Publication Date: 2004 Jan |
Date Detail:
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Created Date: 2003-12-24 Completed Date: 2004-02-05 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 0421041 Medline TA: Br J Ophthalmol Country: England |
Other Details:
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Languages: eng Pagination: 72-4 Citation Subset: IM |
Affiliation:
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Keck School of Medicine, University of Southern California, CA, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Age Factors Aged Body Mass Index Female Graves Disease / blood*, etiology, surgery Humans Hypercholesterolemia / complications Male Middle Aged Ophthalmologic Surgical Procedures Retrospective Studies Risk Factors Sex Factors Thyroid Hormones / blood* |
| Grant Support | |
ID/Acronym/Agency:
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EY 03040/EY/NEI NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Thyroid Hormones |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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