Document Detail

The regional curare test and electrophysiologic diagnosis of myasthenia gravis: further studies.
MedLine Citation:
PMID:  263986     Owner:  NLM     Status:  MEDLINE    
Five hundred consecutive patients were evaluated for myasthenia gravis with repetitive stimulation of the median and ulnar nerves. Axillary nerve stimulation and repeated stimulation of wrist nerves following regional curare administration to the hand were performed when necessary. Abnormal responses were seen in 95% of 297 patients with generalized disease and in 35% of 54 patients with ocular disease, all of whom were clinically responsive to anticholinesterases. Identical responses were also seen in 32% of 124 patients with possible generalized disease, all of whom lacked clinical responsiveness to anticholinesterases. Abnormalities occurred following regional curare administration in 29% of 224 patients with normal responses during repetitive stimulation alone. This program for evaluating patients with suspected myasthenia gravis continues to be successful, safe, and practical.
S H Horowitz; M Sivak
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Muscle & nerve     Volume:  1     ISSN:  0148-639X     ISO Abbreviation:  Muscle Nerve     Publication Date:    1978 Sep-Oct
Date Detail:
Created Date:  1987-01-06     Completed Date:  1987-01-06     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7803146     Medline TA:  Muscle Nerve     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  432-4     Citation Subset:  IM    
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MeSH Terms
Curare / diagnostic use*
Myasthenia Gravis / diagnosis*
Reg. No./Substance:

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