Document Detail


The recognition, physiology, and treatment of medication-induced methemoglobinemia: a case report.
MedLine Citation:
PMID:  17900210     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Dapsone is a leprostatic agent commonly prescribed for the management of leprosy, malaria, and the immunosuppression-induced infections of Pneumocystis carinii and Toxoplasma gondii. In susceptible patients, methemoglobinemia, a potentially life-threatening event, can occur. We report a case of dapsone-induced methemoglobinemia which was observed during general anesthesia for the management of a fractured mandible. The pathophysiology, diagnosis, and management of dapsone-induced methemoglobinemia will be discussed.
Authors:
Michael D Turner; Vasiliki Karlis; Robert S Glickman
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Anesthesia progress     Volume:  54     ISSN:  0003-3006     ISO Abbreviation:  Anesth Prog     Publication Date:  2007  
Date Detail:
Created Date:  2007-09-28     Completed Date:  2007-12-06     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0043533     Medline TA:  Anesth Prog     Country:  United States    
Other Details:
Languages:  eng     Pagination:  115-7     Citation Subset:  D    
Affiliation:
Department of Oral and Maxillofacial Surgery, New York University College of Dentistry, New York, New York 10010-4086, USA. mdt4@nyu.edu
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MeSH Terms
Descriptor/Qualifier:
Anesthesia, General / adverse effects*
Dapsone / adverse effects*
Female
Humans
Leprostatic Agents / adverse effects*
Mandibular Fractures / surgery
Methemoglobinemia / chemically induced*,  diagnosis
Middle Aged
Chemical
Reg. No./Substance:
0/Leprostatic Agents; 80-08-0/Dapsone
Comments/Corrections

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