| A reappraisal of the measurement of glomerular filtration rate in pre-term infants. | |
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MedLine Citation:
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PMID: 1497999 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Thirty-seven single-injection polyfructosan-S (PF-S, Inutest) and 98 continuous-infusion PF-S/creatinine clearance studies were performed in 39 sick very low birth weight infants. The single-injection clearance method for measuring glomerular filtration rate has been shown to be a reliable technique if sampling is continued for 8 h or more and the PF-S (Inutest) assay is sensitive, accurate and precise. The continuous-infusion clearance method is also valid if the infusion is continued for more than 24 h and preceded by a loading dose in the form of a double-rate infusion for 8 h. Creatinine clearance is usually less than PF-S clearance, the mean ratio being 0.91, suggesting that there is some creatinine reabsorption in the renal tubule in sick very low birth weight infants. |
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Authors:
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B H Wilkins |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Pediatric nephrology (Berlin, Germany) Volume: 6 ISSN: 0931-041X ISO Abbreviation: Pediatr. Nephrol. Publication Date: 1992 Jul |
Date Detail:
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Created Date: 1992-09-17 Completed Date: 1992-09-17 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8708728 Medline TA: Pediatr Nephrol Country: GERMANY |
Other Details:
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Languages: eng Pagination: 323-7 Citation Subset: IM |
Affiliation:
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Department of Child Health, Bristol University, UK. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Creatinine
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blood,
urine Fructans / pharmacokinetics* Glomerular Filtration Rate Humans Infant, Low Birth Weight / metabolism* Infant, Newborn Infant, Premature, Diseases / metabolism* Inulin / pharmacokinetics Kidney Glomerulus / metabolism Reproducibility of Results Sensitivity and Specificity |
| Chemical | |
Reg. No./Substance:
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0/Fructans; 39421-73-3/polyfructosan; 60-27-5/Creatinine; 9005-80-5/Inulin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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