| The real value of lower esophageal sphincter measurement for predicting acid gastroesophageal reflux or Barrett's esophagus. | |
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MedLine Citation:
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PMID: 16137594 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The study goal was to ascertain the true value of lower esophageal sphincter measurement in order to establish the risk of presenting gastroesophageal reflux or Barrett's esophagus. Of 671 patients assessed for symptoms of gastroesophageal reflux, 459 were included in a prospective study, practicing esophagogastroscopy, esophageal manometry, and 24-hour pH-metry. The risks of presenting a pathologic DeMeester score or Barrett's esophagus were estimated according to different values for the lower esophageal sphincter parameters. The risk of a pathologic DeMeester score only increased when pressure was less than 6 mm Hg, total length was less than 2 cm, or abdominal length was less than 1 cm; regardless of which parameter was affected, the risk being greater when the three parameters were altered (odds ratio=2.4, 3.1, and 4 for one, two, and three altered parameters). Male sex, sphincter pressure, and DeMeester score were associated with Barrett's esophagus (P<0.05) but not total or abdominal length. Pressure and total and abdominal lengths have a similar influence over establishing the risk of pathologic acid reflux, but only pressure may indicate the risk of Barrett's esophagus. |
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Authors:
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Oscar Alonso; Diego Hernández; Enrique Moreno; Alejandro Manrique; Almudena Moreno; Alvaro García-Sesma; Jorge Calvo |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract Volume: 9 ISSN: 1091-255X ISO Abbreviation: J. Gastrointest. Surg. Publication Date: 2005 Sep-Oct |
Date Detail:
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Created Date: 2005-09-02 Completed Date: 2006-01-27 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9706084 Medline TA: J Gastrointest Surg Country: United States |
Other Details:
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Languages: eng Pagination: 973-9 Citation Subset: IM |
Affiliation:
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Department of Surgery and Abdominal Organ Transplantation, 12 de Octubre University Hospital, Madrid, Spain. montsemc@jazzfree.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Age Factors Aged Barrett Esophagus / diagnosis* Esophageal Sphincter, Lower / pathology* Esophageal pH Monitoring Esophagoscopy Female Forecasting Gastroesophageal Reflux / diagnosis* Gastroscopy Humans Male Manometry Middle Aged Pressure Prospective Studies Risk Factors Sex Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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