Document Detail

Lecithin/sphingomyelin ratios centrifuged and uncentrifuged amniotic fluid.
MedLine Citation:
PMID:  568387     Owner:  NLM     Status:  MEDLINE    
The literature suggests that the presence of cellular debris and sediment in amniotic fluid samples may alter the value of the lecithin/sphingomyelin (L/S) ratios, with a loss of as much as 75 percent of the surface-active lecithin1 and consequently a marked change in the L/S ratio. We wish to report our findings on 22 amniotic fluids obtained by transabdominal amniocentesis and analyzed with and without preliminary centrifugation. We find the L/S ratio is indeed unaltered by centrifugation. However, the actual amounts of lecithin and sphingomyelin appear to be lower in centrifuged samples.
K P Railsback; W S Haller
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of medical technology     Volume:  44     ISSN:  0002-9335     ISO Abbreviation:  Am J Med Technol     Publication Date:  1978 Sep 
Date Detail:
Created Date:  1978-12-27     Completed Date:  1978-12-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370505     Medline TA:  Am J Med Technol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  852-4     Citation Subset:  IM    
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MeSH Terms
Amniotic Fluid / analysis*
Phosphatidylcholines / analysis*
Sphingomyelins / analysis*
Reg. No./Substance:
0/Phosphatidylcholines; 0/Sphingomyelins

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