Document Detail


The rationale of magnesium as alternative therapy for patients with acute myocardial infarction without thrombolytic therapy.
MedLine Citation:
PMID:  8694008     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Only one third of hospitalized patients with acute myocardial infarction receive thrombolytic therapy despite its proven benefits on outcomes. Elderly patients, for example, have a greater risk of death after myocardial infarction, but studies demonstrate that thrombolytic therapy is less likely to be used in older patients. Intravenous magnesium supplementation, both theoretically and experimentally, has been demonstrated to decrease myocardial damage and reduce the mortality rate in subsets of patients, including the elderly and/or patients not suitable for thrombolysis, if it is administered before reperfusion occurs. The aim of this study is to review the rationale for patients with acute myocardial infarction without thrombolytic therapy.
Authors:
M Shechter; H Hod; E Kaplinsky; B Rabinowitz
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  American heart journal     Volume:  132     ISSN:  0002-8703     ISO Abbreviation:  Am. Heart J.     Publication Date:  1996 Aug 
Date Detail:
Created Date:  1996-08-29     Completed Date:  1996-08-29     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0370465     Medline TA:  Am Heart J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  483-6; discussion 496-502     Citation Subset:  AIM; IM    
Affiliation:
Heart Institute, Sheba Medical Center, Tel Hashomer, Israel.
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MeSH Terms
Descriptor/Qualifier:
Calcium Channel Blockers / pharmacology,  therapeutic use*
Clinical Trials as Topic
Humans
Magnesium Sulfate / pharmacology,  therapeutic use*
Myocardial Infarction / drug therapy*
Treatment Outcome
Chemical
Reg. No./Substance:
0/Calcium Channel Blockers; 7487-88-9/Magnesium Sulfate

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