| The rationale for caries prevention through the use of sugar substitutes. | |
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MedLine Citation:
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PMID: 3858226 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The emergence of S. mutans in the plaque flora appears to have depended upon the ability of the organism to sequester sucrose from dietary sources, particularly from between-meal, snack-type foods. S. mutans appears to have a pH optimum at about the pH required for tooth solution to begin. This specialization which makes S. mutans cariogenic, also makes it vulnerable to dietary regimens that contain few or no sucrose snacks. As snacks are consumed by youngsters, primarily for pleasure, the use of pleasant tasting sucrose substitutes, that cannot be fermented by the plaque flora and especially by S. mutans, constitutes a viable tactic for caries control. The potential of this approach was demonstrated by the 80 per cent reduction of caries relative to a sucrose control which was observed with a xylitol chewing gum in the Turku study. |
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Authors:
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W J Loesche |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: International dental journal Volume: 35 ISSN: 0020-6539 ISO Abbreviation: Int Dent J Publication Date: 1985 Mar |
Date Detail:
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Created Date: 1985-06-25 Completed Date: 1985-06-25 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0374714 Medline TA: Int Dent J Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 1-8 Citation Subset: D; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acids
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metabolism Chewing Gum Dental Caries / microbiology, physiopathology, prevention & control* Dental Plaque / microbiology, physiopathology Food Habits Humans Hydrogen-Ion Concentration Saliva / physiology Streptococcus mutans / metabolism, physiology Sweetening Agents / therapeutic use* Tooth Remineralization Xylitol / therapeutic use |
| Chemical | |
Reg. No./Substance:
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0/Acids; 0/Chewing Gum; 0/Sweetening Agents; 87-99-0/Xylitol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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