Document Detail

The estriol/creatinine ratio in a random urine sample as a screening test.
MedLine Citation:
PMID:  683629     Owner:  NLM     Status:  MEDLINE    
The estriol/creatinine ratio was determined in a first morning urine sample in 1808 pregnancies in the 32nd week of gestation. The ratio obtained correlated closely with birthweight and showed a linear increase with percentile birthweight group. There was a 25-fold increase in perinatal mortality in those pregnancies with a ratio below the tenth percentile; all pregnancies ending in stillbirths with birthweight below the tenth percentile gave such a ratio. The single estrogen/creatinine ratio allowed the early detection of a group of pregnancies at high risk of intrauterine growth retardation or major total abnormality without inconvenience for the patient.
C J Hutchins
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  52     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  1978 Jul 
Date Detail:
Created Date:  1978-10-18     Completed Date:  1978-10-18     Revised Date:  2009-10-26    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  46-9     Citation Subset:  AIM; IM    
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MeSH Terms
Birth Weight
Creatinine / urine*
Estriol / urine*
Fetal Death / epidemiology
Fetal Growth Retardation / diagnosis*
Gestational Age
Infant Mortality
Infant, Newborn
Prenatal Diagnosis / methods*
Reg. No./Substance:
50-27-1/Estriol; 60-27-5/Creatinine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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