Document Detail

The rate of severe preeclampsia is increased in triplet as compared to twin gestations.
MedLine Citation:
PMID:  9259940     Owner:  NLM     Status:  MEDLINE    
The objective of this study was to determine if the rate of preeclampsia is increased in triplet as compared to twin gestations. Fifty-three triplet pregnancies between 1986 and 1993 at The New York Hospital-Cornell Medical Center were reviewed. These were matched for maternal age, parity, and race to twin gestations (N = 53) from the same population. Severe preeclampsia was defined by standard criteria. Student's t-test, Fisher exact test, and Chi-square were used for statistical analysis. The rate of severe preeclampsia was increased significantly in the triplet group 12 of 53 (22.6%) as compared with the twin group 3 of 53 (5.7%) (OR = 4.9, 95% CI 1.2-23.5, p = 0.02). The rate of overall preeclampsia was not significantly different in the triplet 18 of 53 (33.96%) or twin 12 of 53 (22.6%) groups. In this retrospective, case-controlled study, the rate of severe pre-eclampsia was significantly increased in triplet gestations as compared to twins although the overall rate of preeclampsia was not. This information may be useful in counseling patients with high order multifetal gestations.
J M Mastrobattista; D W Skupski; M Monga; J D Blanco; P August
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  American journal of perinatology     Volume:  14     ISSN:  0735-1631     ISO Abbreviation:  Am J Perinatol     Publication Date:  1997 May 
Date Detail:
Created Date:  1997-09-04     Completed Date:  1997-09-04     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8405212     Medline TA:  Am J Perinatol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  263-5     Citation Subset:  IM    
Department of Obstetrics, University of Texas Medical School at Houston 77030, USA.
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MeSH Terms
Case-Control Studies
Data Interpretation, Statistical
Gestational Age
Infant, Newborn
Maternal Age
Pre-Eclampsia / epidemiology*,  etiology
Pregnancy Outcome
Retrospective Studies

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