| The rate of primary hypothyroidism in diabetic patients is greater than in the non-diabetic population. An observational study. | |
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MedLine Citation:
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PMID: 22204860 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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BACKGROUND AND OBJECTIVE: The aim of our study was to identify the rate of diabetic patients treated for hypothyroidism and compare them with a group without type 2 diabetes mellitus (T2DM). PATIENTS AND METHODS: We reviewed the computerized clinical records of 5161 patients. We identified diabetic patients treated with l-thyroxine. We compared the prevalence of PH with those patients under treatment with levothyroxine without T2DM. We excluded patients with a thyroid neoplasia, thyroid surgery, panhypopituitarism, or surgical complications of multinodular goiter or a thyroid nodule. Subclinical hypothyroidism was not considered. RESULTS: We included 1848 adult patients with T2DM in the study group, 58% women and 42% men. For the control group, we included 3313 non-diabetic patients, 55% women and 45% men. The mean age in the study group was 52±7 years, and 47±4 years in the control group (p<.001). The rate of hypothyroidism in the study group was 5.7%, and in the control group 1.8% (odds ratio of 3.45; 95% confidence interval 2.51-4.79) (p<.001). CONCLUSION: A strong association between T2DM and hypothyroidism was found. We recommend a thyroid profile in all patients with T2DM, similar to the recommendation in type 1 diabetes mellitus. |
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Authors:
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Hector-Eloy Tamez-Pérez; Esteban Martínez; Dania L Quintanilla-Flores; Alejandra L Tamez-Peña; Hugo Gutiérrez-Hermosillo; Enrique Díaz de León-González |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-12-26 |
Journal Detail:
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Title: Medicina clinica Volume: - ISSN: 0025-7753 ISO Abbreviation: - Publication Date: 2011 Dec |
Date Detail:
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Created Date: 2011-12-29 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0376377 Medline TA: Med Clin (Barc) Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2011 Elsevier España, S.L. All rights reserved. |
Affiliation:
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Subdirección de Investigación, Facultad de Medicina U.A.N.L., Monterrey, NL, Mexico. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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