| A rat model for monitoring homograft rejection of the lung. | |
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MedLine Citation:
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PMID: 3532425 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A new surgical procedure was devised for the experimental homograft of the lung. The pulmonary artery and vein and bronchus were anastomosed under the operation microscope using interrupted sutures in group W (30 outbred Wistar rats) and continuous sutures in group F (7 inbred F344/Ducrj Rats). Mean ischemia time during the operation was 95.3 +/- 10.3 min in the group W and 55.6 +/- 5.8 in group F. Eight out of 30 rats (27%) of group W and all rats of group F survived more than 24 hr after the surgery. Pulmonary functions of grafted lungs were evaluated by serial x-rays and the perfusion ratio was 27.4 +/- 11.6% (mean +/- S.D.) in group W and 25.4 +/- 7.7% in group F. A patent opening of the hilar anastomosis in these rats was confirmed at autopsy. This model with continuous suture would be useful for the rat lung transplantation. |
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Authors:
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T Kondo; F Shionozaki; S Fujimura; A Yamauchi; M Handa; T Okabe; R Saito; T Ichinose; Y Shiraishi; T Nakada |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The Tohoku journal of experimental medicine Volume: 149 ISSN: 0040-8727 ISO Abbreviation: Tohoku J. Exp. Med. Publication Date: 1986 Jul |
Date Detail:
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Created Date: 1986-11-10 Completed Date: 1986-11-10 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0417355 Medline TA: Tohoku J Exp Med Country: JAPAN |
Other Details:
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Languages: eng Pagination: 323-8 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Graft Rejection* Lung Transplantation* Male Models, Biological Rats Rats, Inbred Strains Transplantation, Homologous |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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