| A rat brain MRI template with digital stereotaxic atlas of fine anatomical delineations in paxinos space and its automated application in voxel-wise analysis. | |
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MedLine Citation:
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PMID: 22287270 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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This study constructs a rat brain T(2) -weighted magnetic resonance imaging template including olfactory bulb and a compatible digital atlas. The atlas contains 624 carefully delineated brain structures based on the newest (2005) edition of rat brain atlas by Paxinos and Watson. An automated procedure, as an SPM toolbox, was introduced for spatially normalizing individual rat brains, conducting statistical analysis and visually localizing the results in the Atlas coordinate space. The brain template/atlas and the procedure were evaluated using functional images between rats with the right side middle cerebral artery occlusion (MCAO) and normal controls. The result shows that the brain region with significant signal decline in the MCAO rats was consistent with the occlusion position. Hum Brain Mapp, 2012. © 2012 Wiley Periodicals, Inc. |
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Authors:
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Binbin Nie; Kewei Chen; Shujun Zhao; Junhua Liu; Xiaochun Gu; Qunli Yao; Jiaojie Hui; Zhijun Zhang; Gaojun Teng; Chunjie Zhao; Baoci Shan |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-1-30 |
Journal Detail:
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Title: Human brain mapping Volume: - ISSN: 1097-0193 ISO Abbreviation: - Publication Date: 2012 Jan |
Date Detail:
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Created Date: 2012-1-30 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9419065 Medline TA: Hum Brain Mapp Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2012 Wiley Periodicals, Inc. |
Affiliation:
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Key Laboratory of Nuclear Analytical Techniques, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, China. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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