Document Detail


A rare incidental finding in a case of painless jaundice.
MedLine Citation:
PMID:  18410831     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Portal vein thrombosis secondary to protein C deficiency is a rare finding. Diagnosing a portal vein thrombosis itself is difficult due to nonspecific symptoms such as nausea, vomiting, anorexia, and weight loss. Proving that a protein C deficiency is the cause of a portal vein thrombosis is even more difficult as an extensive and thorough workup is required to rule out malignancies, myeloproliferative disorders, and hypercoaguable states which can all lead to thromboses. Patients require anticoagulation to prevent two dangerous complications of portal vein thrombosis; portal hypertension leading to esophageal varices with massive hemetemesis and extension of thrombus from the portal vein into the mesenteric veins leading to intestinal ischemia and death. In this case report, we present a patient with the complaint of painless jaundice who was found to have an incidental finding of portal vein thrombosis secondary to protein C deficiency. The different etiologies of portal vein thrombosis, along with diagnosis and treatment options will be discussed and highlighted.
Authors:
Sundip N Patel; Brigitte M Baumann; Michael C Farner; Michael C Farmer
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The American journal of emergency medicine     Volume:  26     ISSN:  1532-8171     ISO Abbreviation:  Am J Emerg Med     Publication Date:  2008 May 
Date Detail:
Created Date:  2008-04-15     Completed Date:  2008-04-25     Revised Date:  2008-12-01    
Medline Journal Info:
Nlm Unique ID:  8309942     Medline TA:  Am J Emerg Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  516.e1-2     Citation Subset:  IM    
Affiliation:
Department of Emergency Medicine, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School-Camden, Cooper University Hospital, Camden, NJ 08103, USA.
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MeSH Terms
Descriptor/Qualifier:
Choledocholithiasis / complications*
Humans
Incidental Findings
Jaundice / etiology*
Male
Middle Aged
Portal Vein*
Protein C Deficiency / complications*
Venous Thrombosis / etiology*
Comments/Corrections
Erratum In:
Am J Emerg Med. 2009 Jan;27(1):126.
Note: Farmer, Michael C [corrected to Farner, Michael C]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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