| A rare incidental finding in a case of painless jaundice. | |
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MedLine Citation:
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PMID: 18410831 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Portal vein thrombosis secondary to protein C deficiency is a rare finding. Diagnosing a portal vein thrombosis itself is difficult due to nonspecific symptoms such as nausea, vomiting, anorexia, and weight loss. Proving that a protein C deficiency is the cause of a portal vein thrombosis is even more difficult as an extensive and thorough workup is required to rule out malignancies, myeloproliferative disorders, and hypercoaguable states which can all lead to thromboses. Patients require anticoagulation to prevent two dangerous complications of portal vein thrombosis; portal hypertension leading to esophageal varices with massive hemetemesis and extension of thrombus from the portal vein into the mesenteric veins leading to intestinal ischemia and death. In this case report, we present a patient with the complaint of painless jaundice who was found to have an incidental finding of portal vein thrombosis secondary to protein C deficiency. The different etiologies of portal vein thrombosis, along with diagnosis and treatment options will be discussed and highlighted. |
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Authors:
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Sundip N Patel; Brigitte M Baumann; Michael C Farner; Michael C Farmer |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: The American journal of emergency medicine Volume: 26 ISSN: 1532-8171 ISO Abbreviation: Am J Emerg Med Publication Date: 2008 May |
Date Detail:
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Created Date: 2008-04-15 Completed Date: 2008-04-25 Revised Date: 2008-12-01 |
Medline Journal Info:
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Nlm Unique ID: 8309942 Medline TA: Am J Emerg Med Country: United States |
Other Details:
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Languages: eng Pagination: 516.e1-2 Citation Subset: IM |
Affiliation:
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Department of Emergency Medicine, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School-Camden, Cooper University Hospital, Camden, NJ 08103, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Choledocholithiasis
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complications* Humans Incidental Findings Jaundice / etiology* Male Middle Aged Portal Vein* Protein C Deficiency / complications* Venous Thrombosis / etiology* |
| Comments/Corrections | |
Erratum In:
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Am J Emerg Med. 2009 Jan;27(1):126. Note: Farmer, Michael C [corrected to Farner, Michael C] |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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