| A rare combination of recurrent pneumonia, diarrhoea, and visual loss in a patient after thymectomy: good syndrome. | |
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MedLine Citation:
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PMID: 21135430 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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This report describes a 68-year-old Chinese man who was diagnosed with Good syndrome 6 years after initial presentation when he underwent thymectomy. He presented with recurrent pneumonia, diarrhoea, weight loss, and visual symptoms. Extensive examination for anaemia and neutropenia was done, yet no conclusive diagnosis could be derived. During his last admission for pneumonia, his history of AB thymoma suggested the possibility of Good syndrome. Immunological testing revealed low T cells, absent B cells, and low immunoglobulin M and immunoglobulin G levels. Moreover, he had histologically identified cytomegalovirus pneumonia, cytomegalovirus colitis, and fundoscopic features of cytomegalovirus retinitis. He was treated with a 2-week course of intravenous ganciclovir, lifelong oral valganciclovir, and monthly immunoglobulin infusion. It took 6 years for the diagnosis to be established, therefore, early attention and vigorous search for such potentially treatable conditions in post-thymectomy patients presenting with recurrent infections is recommended. |
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Authors:
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J K Y Ho; M M L Wong; T K F Tai; D M W Tse |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Hong Kong medical journal = Xianggang yi xue za zhi / Hong Kong Academy of Medicine Volume: 16 ISSN: 1024-2708 ISO Abbreviation: Hong Kong Med J Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-12-07 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9512509 Medline TA: Hong Kong Med J Country: China |
Other Details:
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Languages: eng Pagination: 493-6 Citation Subset: IM |
Affiliation:
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Department of Medicine, Caritas Medical Centre, Shamshuipo, Kowloon, Hong Kong. hoky2@ha.org.hk |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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