| A rare cause of dyspnea and arterial hypoxemia. | |
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MedLine Citation:
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PMID: 9404771 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Platypnea-orthodeoxia is a rare pattern of dyspnea with arterial hypoxemia. Platypnea is defined as dyspnea induced by upright posture, and it is relieved by the recumbent position. Orthodeoxia refers to arterial desaturation resulting from assuming an erect or upright position. The case reported involves a 59-year-old man with profound, unexplained dyspnea despite extensive investigation performed at the referring institution. The difficulty in diagnosis persisted until it was recognized that the investigations, in having been performed under "standard" (supine) conditions, were insufficient and therefore misleading. Despite normal supine intracardiac pressures, a patent foramen ovale was shown to give rise to a large orthostatic intracardiac shunt, demonstrated by means of an echocardiogram performed with the patient supine and upright. Surgical closure of the foramen was followed by dramatic clinical improvement. Among dyspneic patients, discernment of a pattern of platypnea and orthodeoxia is key to effective evaluation. |
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Authors:
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T Al Khouzaie; J R Busser |
Publication Detail:
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Type: Case Reports; Journal Article; Review |
Journal Detail:
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Title: Chest Volume: 112 ISSN: 0012-3692 ISO Abbreviation: Chest Publication Date: 1997 Dec |
Date Detail:
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Created Date: 1998-01-06 Completed Date: 1998-01-06 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0231335 Medline TA: Chest Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1681-2 Citation Subset: AIM; IM |
Affiliation:
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Department of Medicine, University of British Columbia and Vancouver Hospital and Health Sciences Centre, Canada. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anoxia
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diagnosis,
etiology* Chronic Disease Diagnosis, Differential Dyspnea / diagnosis, etiology* Echocardiography Heart Septal Defects, Atrial / complications, diagnosis Humans Male Middle Aged Posture Syndrome |
| Comments/Corrections | |
Comment In:
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Chest. 1997 Dec;112(6):1449-51
[PMID:
9404736
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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