| A rare case of internal jugular vein aneurysmal degeneration in a type 1 neurofibromatosis complicated by potentially life-threatening thrombosis. | |
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MedLine Citation:
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PMID: 21684713 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Type 1 neurofibromatosis (NF1) is an autosomal dominant disorder characterized by multiple forms of neural crest cell proliferation. Associated venous malformations are extremely rare. We present a case of a giant thrombosed internal jugular aneurysm with brachiocephalic vein thrombosis in an NF1 patient. Surgical correction required prophylactic left brachiocephalic vein ligation, aneurysm evacuation, and proximal jugular vein ligation. Extreme vein friability caused severe intraoperative bleeding. Vein wall histology confirmed neurofibromatosis infiltration. Jugular vein aneurysm and infiltration in NF1, although exceedingly rare, can pose a serious threat to the patient during surgical correction, with major vessel thrombosis enhancing morbidity and mortality. |
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Authors:
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Mirko Belcastro; Andrea Palleschi; Riccardo A Trovato; Ruggero Landini; Maurizio Di Bisceglie; Armando Natale |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of vascular surgery Volume: 54 ISSN: 1097-6809 ISO Abbreviation: J. Vasc. Surg. Publication Date: 2011 Oct |
Date Detail:
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Created Date: 2011-10-05 Completed Date: 2011-11-18 Revised Date: 2012-10-03 |
Medline Journal Info:
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Nlm Unique ID: 8407742 Medline TA: J Vasc Surg Country: United States |
Other Details:
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Languages: eng Pagination: 1170-3 Citation Subset: IM |
Copyright Information:
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Copyright © 2011 Society for Vascular Surgery. Published by Mosby, Inc. All rights reserved. |
Affiliation:
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Vascular Surgery Unit, Misericordia Hospital, Grosseto, Italy. mirkoblc@fastwebnet.it |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aneurysm, Ruptured
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diagnosis,
etiology*,
surgery Female Humans Jugular Veins* / pathology, radiography, surgery Ligation Middle Aged Neurofibromatosis 1 / complications*, diagnosis Tomography, X-Ray Computed Treatment Outcome Vascular Surgical Procedures Venous Thrombosis / diagnosis, etiology*, surgery |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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