| A rare case of ciprofloxacin-induced bilateral rupture of the Achilles tendon. | |
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MedLine Citation:
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PMID: 21686678 Owner: NLM Status: PubMed-not-MEDLINE |
Abstract/OtherAbstract:
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Fluoroquinolone antibiotics have been widely used for over 25 years. Their key adverse effect is tendinopathy. A 76-year-old woman developed bilateral Achilles tendinopathy on the fourth day of fluoroquinolone use. Her doctor advised her to complete the course; however, she went on to sustain bilateral tendoachilles rupture. The patient undertook self-referral to a Primary Care Musculoskeletal Assessment Service, where bilateral Achilles tendon rupture was confirmed by ultrasonography. Surgical repair of both tendons was undertaken. Several months postoperatively the patient was discharged. Fluoroquinolone-related tendinopathy can occur within hours of commencing the medication or up to 6 months post cessation. The incidence of Achilles tendon disorders significantly outweighs pathology in other tendons. Men are up to four times more susceptible than women, hence bilateral rupture in a 76-year-old woman is rare. Patients prescribed fluoroquinolones presenting with tendinopathy require consideration of dose reduction or cessation of fluoroquinolone therapy. |
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Authors:
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Trevor G Lewis |
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Publication Detail:
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Type: Journal Article Date: 2009-03-05 |
Journal Detail:
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Title: BMJ case reports Volume: 2009 ISSN: 1757-790X ISO Abbreviation: BMJ Case Rep Publication Date: 2009 |
Date Detail:
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Created Date: 2011-06-20 Completed Date: 2011-11-10 Revised Date: 2013-04-02 |
Medline Journal Info:
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Nlm Unique ID: 101526291 Medline TA: BMJ Case Rep Country: England |
Other Details:
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Languages: eng Pagination: - Citation Subset: - |
Affiliation:
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Knowsley PCT, Physiotherapy Department, Whiston Hospital, Warrington Road, Merseyside, L35 5DR, UK. |
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