| A rapid method for the detection of circulating immune complexes in biological fluids by counterimmunoelectrophoresis. | |
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MedLine Citation:
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PMID: 7123115 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Owing to their great content in neuraminic acid and/or nucleic acids, most of the circulating immune complexes run significantly faster as unbound gammaglobulins during agar gel electrophoresis. Therefore, because of their immunoglobulin components they can be easily detected in the alpha-1, inter-alpha, alpha-2 and beta fractions with monospecific anti-Ig-sera by counterimmunoelectrophoresis. The presence of Factor III of complement and of fibrinogen, in some cryoglobulins can be proved in the some way. Finally, nucleic acid content (both RNA and DNA), and presence of neuraminic acid in precipitated immune complexes can be demonstrated by usual histologic methods (Giemsa, methyl green-pyronine, PAS or Aminoff) on washed and dried slides. |
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Authors:
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E J Módy |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Médecine interne Volume: 20 ISSN: 0377-1202 ISO Abbreviation: Med Interne Publication Date: 1982 Apr-Jun |
Date Detail:
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Created Date: 1982-12-02 Completed Date: 1982-12-02 Revised Date: 2000-12-18 |
Medline Journal Info:
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Nlm Unique ID: 7506353 Medline TA: Med Interne Country: ROMANIA |
Other Details:
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Languages: eng Pagination: 165-6 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Antigen-Antibody Complex
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analysis* Counterimmunoelectrophoresis* Immunoelectrophoresis* |
| Chemical | |
Reg. No./Substance:
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0/Antigen-Antibody Complex |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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