| A ranking system for the evaluation of intersex condition in European flounder (Platichthys flesus). | |
| | |
MedLine Citation:
|
PMID: 15648756 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Intersex (ovotestis) is the condition whereby an individual possesses oocytes, at varying degrees of severity, within the normal testicular tissue and is regarded as an endpoint of endocrine disruption in male fish. The occurrence of intersex has been linked with exposure to endocrine-disrupting compounds present in the environment, which are thought to mimic the actions of the female sex hormone 17-beta-oestradiol. Using stained histological sections of archived cases of intersex from European flounder (Platichthys flesus), this study developed a grading method to assess the extent of the condition. This was termed the ovotestis severity index (OSI). The OSI utilizes the distribution pattern (focal, diffuse, cluster, zonal) and type of oocyte (previtellogenic, cortical alveolar, vitellogenic) to assign a severity rating to each intersex fish. A high OSI refers to fish with testicular material almost completely replaced with mature (vitellogenic) oocytes, and lower scores indicate those fish with small numbers of immature (previtellogenic) oocytes. The development of this index provides pathologists with a robust tool for the grading of the intersex condition in European flounder and potentially in other fish species. |
| | |
Authors:
|
Kelly S Bateman; Grant D Stentiford; Stephen W Feist |
Related Documents
:
|
12065926 - Endocrine disrupters and testicular dysgenesis syndrome. 22295896 - Into and out of africa - taking over from denis burkitt. 22763196 - Antiangiogenic drugs for colorectal cancer: exploring new possibilities. 22898786 - Effects of changes in diagnosis and registration on time trends in recorded childhood c... 18406516 - Pro-inflammatory prostaglandins and progression of colorectal cancer. 23032576 - Cytochrome p1b1 gene (cyp1b1) polymorphisms and ovarian cancer risk: a meta-analysis. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Environmental toxicology and chemistry / SETAC Volume: 23 ISSN: 0730-7268 ISO Abbreviation: Environ. Toxicol. Chem. Publication Date: 2004 Dec |
Date Detail:
|
Created Date: 2005-01-14 Completed Date: 2005-11-15 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 8308958 Medline TA: Environ Toxicol Chem Country: United States |
Other Details:
|
Languages: eng Pagination: 2831-6 Citation Subset: IM |
Affiliation:
|
Centre for Environment, Fisheries and Aquaculture Science, Weymouth Laboratory, Barrack Road, The Nothe, Weymouth, Dorset, DT4 8UB, United Kingdom. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Environmental Monitoring / methods Flounder / abnormalities* Great Britain Hermaphroditism / chemically induced, classification*, veterinary Male Oocytes / pathology Testis / abnormalities |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Subcellular accumulation of polychlorinated biphenyls in the green alga Chlamydomonas reinhardtii.
Next Document: Assessment of the toxicity of triasulfuron and its photoproducts using aquatic organisms.