Document Detail


A randomized trial of prenatal ultrasonographic screening: impact on maternal management and outcome. RADIUS (Routine Antenatal Diagnostic Imaging with Ultrasound) Study Group.
MedLine Citation:
PMID:  8372849     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: This randomized clinical trial of 15,530 women was designed to test the hypothesis that screening ultrasonography in low-risk pregnancies would improve perinatal outcome. A secondary hypothesis addressed in this article was that screening ultrasonography would have a favorable impact on maternal management or outcome. STUDY DESIGN: Pregnant women without a specific indication for ultrasonographic examination in early pregnancy were randomly assigned to have either two screening sonograms or conventional obstetric care. Pregnancy interventions and maternal outcomes were compared in the two groups. RESULTS: No significant differences were found in maternal outcomes. Use of ultrasonography was markedly higher in the screened group. The rates of induced abortion, amniocentesis, tests of fetal well-being, external version, induction, and cesarean section and the distribution of total hospital days were similar in the two groups. Use of tocolytics and the rate of postdate pregnancy were both slightly lower in the screened group. CONCLUSION: Screening ultrasonography resulted in no clinically significant benefit.
Authors:
M L LeFevre; R P Bain; B G Ewigman; F D Frigoletto; J P Crane; D McNellis
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  169     ISSN:  0002-9378     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  1993 Sep 
Date Detail:
Created Date:  1993-10-14     Completed Date:  1993-10-14     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  483-9     Citation Subset:  AIM; IM    
Affiliation:
Department of Family and Community Medicine, University of Missouri, Columbia 65212.
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MeSH Terms
Descriptor/Qualifier:
Female
Fetal Growth Retardation / ultrasonography
Fetal Macrosomia / ultrasonography
Gestational Age
Humans
Infant, Newborn
Infant, Small for Gestational Age
Pregnancy
Pregnancy Outcome*
Pregnancy Trimester, Second
Pregnancy Trimester, Third
Pregnancy, Multiple
Prenatal Care*
Ultrasonography, Prenatal*
Grant Support
ID/Acronym/Agency:
HD 19897/HD/NICHD NIH HHS; HD 21017/HD/NICHD NIH HHS; HD 21140/HD/NICHD NIH HHS
Comments/Corrections
Comment In:
Am J Obstet Gynecol. 1994 Aug;171(2):580   [PMID:  8059855 ]
Am J Obstet Gynecol. 1994 Aug;171(2):579-80   [PMID:  8059854 ]
Am J Obstet Gynecol. 1994 Aug;171(2):580-1   [PMID:  8059856 ]
Am J Obstet Gynecol. 1994 Aug;171(2):581-2   [PMID:  8059857 ]
Am J Obstet Gynecol. 1995 Jan;172(1 Pt 1):242-3   [PMID:  7847552 ]

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