Document Detail

A randomized trial comparing lithoclast with an electrokinetic lithotripter in the management of ureteric stones.
MedLine Citation:
PMID:  10619939     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To compare two in situ ballistic lithotripters, the lithoclast and the electrokinetic lithotripter (EKL), both of which can be used through the newer small-bore ureteroscopes, for their ease of use, robustness, fragmentation time, adequacy of fragmentation and stone-free rate. PATIENTS AND METHODS: Forty-six consecutive patients with ureteric stones refractory to treatment by extracorporeal shock wave lithotripsy were randomized to undergo fragmentation using the lithoclast (23 patients) or the EKL (23 patients). One patient was excluded from analysis in the EKL group. The adequacy of fragmentation was recorded, with the degree and significance of proximal migration for each device. After treatment patients were assessed by plain X-ray and the stone-free rate was determined. RESULTS: The mean (median) initial stone burdens in the lithoclast and EKL groups were 69 (50) mm2 and 72 (52) mm2, respectively. The respective mean (median) procedure duration and fragmentation time were 54 (50) min and 90 (49) s in the lithoclast group, and 50 (42.5) min and 87 (52.5) s in the EKL group; the differences were not statistically significant. In four (14%) patients of each group there was significant proximal migration of the stones. The stones were completely fragmented in 17 of 23 (74%) patients in the lithoclast group and 19 of 22 (86%) in the EKL group. There was no fragmentation in one patient in each group. In the lithoclast and EKL groups, 20 of 23 (87%) and 17 of 22 (77%) were rendered stone-free, respectively (P > 0.5). The equipment failed on two occasions in each group. CONCLUSION: In this randomized trial there was no significant difference in the stone-free rate, procedure duration, fragmentation time, proximal stone migration rate and equipment failure between these in situ ballistic lithotripters.
P Menezes; P V Kumar; A G Timoney
Related Documents :
8291879 - Treatment of urinary stones by extracorporeal shock wave lithotripsy.
18643719 - Safety and efficacy of synchronous percutaneous nephrostolithotomy and contralateral ur...
3561289 - Pineal neoplasms and third-ventricular teratomas in niigata (japan) and western austral...
20570319 - One week of nitrofurantoin before percutaneous nephrolithotomy significantly reduces up...
8134579 - Screening-detected and symptomatic ductal carcinoma in situ: mammographic features with...
17469029 - Impact of the degree of hydronephrosis on the efficacy of in situ extracorporeal shock-...
19066939 - Effects of reconstruction methods on a patient's quality of life after a proximal gastr...
21234539 - Patellar resurfacing in total knee arthroplasty for osteoarthritis: a meta-analysis.
9420069 - Pulmonary function and radiographic abnormalities related to neurological outcome after...
Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  BJU international     Volume:  85     ISSN:  1464-4096     ISO Abbreviation:  BJU Int.     Publication Date:  2000 Jan 
Date Detail:
Created Date:  2000-02-24     Completed Date:  2000-02-24     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  100886721     Medline TA:  BJU Int     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  22-5     Citation Subset:  IM    
Bristol Urological Institute, Southmead Hospital, Westbury-on-Trym, UK.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Electric Stimulation Therapy / instrumentation
Lithotripsy / instrumentation*
Middle Aged
Treatment Outcome
Ureteral Calculi / pathology,  therapy*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Radiographic vs surgical size of renal tumours after partial nephrectomy.
Next Document:  Quality of life after radical cystectomy and orthotopic bladder substitution: a comparison between I...