Document Detail

A randomized trial of Citanest with Octapressin for relief of pain associated with laser vaporization of the cervix.
MedLine Citation:
PMID:  2429687     Owner:  NLM     Status:  MEDLINE    
Fifty women undergoing laser vaporization of the cervix for cervical intraepithelial neoplasia were randomly allocated to one of two groups. In one group the patients received no anaesthesia, in the other the ectocervix was infiltrated with 2 ml of Citanest with Octapressin (prilocaine 3% with 0.03 i.u./ml. of felypressin) immediately before the procedure. The pain experienced by each group was assessed immediately after treatment by visual analogue and verbal rating scales. The pain experienced by those women receiving local anaesthesia was significantly reduced as assessed by the visual analogue scale (P = 0.011) and this reduction was not quite significant by the verbal rating scale (P = 0.06). The Citanest group had less troublesome bleeding but the difference in bleeding between the two groups was not significant.
E T Lee; E N Ozumba; J R Bevan
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  British journal of obstetrics and gynaecology     Volume:  93     ISSN:  0306-5456     ISO Abbreviation:  Br J Obstet Gynaecol     Publication Date:  1986 Sep 
Date Detail:
Created Date:  1986-12-17     Completed Date:  1986-12-17     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  7503752     Medline TA:  Br J Obstet Gynaecol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  967-9     Citation Subset:  AIM; IM    
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MeSH Terms
Anesthesia, Local*
Cervix Uteri / physiopathology,  surgery*
Clinical Trials as Topic
Laser Therapy*
Palliative Care*
Random Allocation
Uterine Cervical Neoplasms / physiopathology,  surgery*
Reg. No./Substance:
50-57-7/Lypressin; 56-59-7/Felypressin; 721-50-6/Prilocaine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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