Document Detail

A randomized study of three interventions for aspiration of thin liquids in patients with dementia or Parkinson's disease.
MedLine Citation:
PMID:  18230864     Owner:  NLM     Status:  MEDLINE    
PURPOSE: This study was designed to identify which of 3 treatments for aspiration on thin liquids-chin-down posture, nectar-thickened liquids, or honey-thickened liquids-results in the most successful immediate elimination of aspiration on thin liquids during the videofluorographic swallow study in patients with dementia and/or Parkinson's disease.
METHOD: This randomized clinical trial included 711 patients ages 50 to 95 years who aspirated on thin liquids as assessed videofluorographically. All patients received all 3 interventions in a randomly assigned order during the videofluorographic swallow study.
RESULTS: Immediate elimination of aspiration on thin liquids occurred most often with honey-thickened liquids for patients in each diagnostic category, followed by nectar-thickened liquids and chin-down posture. Patients with most severe dementia exhibited least effectiveness on all interventions. Patient preference was best for chin-down posture followed closely by nectar-thickened liquids.
CONCLUSION: To identify best short-term intervention to prevent aspiration of thin liquid in patients with dementia and/or Parkinson's disease, a videofluorographic swallow assessment is needed. Evidence-based practice requires taking patient preference into account when designing a dysphagic patient's management plan. The longer-term impact of short-term prevention of aspiration requires further study.
Jeri A Logemann; Gary Gensler; Joanne Robbins; Anne S Lindblad; Diane Brandt; Jacqueline A Hind; Steven Kosek; Karen Dikeman; Marta Kazandjian; Gary D Gramigna; Donna Lundy; Susan McGarvey-Toler; Patricia J Miller Gardner
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Journal of speech, language, and hearing research : JSLHR     Volume:  51     ISSN:  1092-4388     ISO Abbreviation:  J. Speech Lang. Hear. Res.     Publication Date:  2008 Feb 
Date Detail:
Created Date:  2008-01-30     Completed Date:  2008-03-19     Revised Date:  2014-09-24    
Medline Journal Info:
Nlm Unique ID:  9705610     Medline TA:  J Speech Lang Hear Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  173-83     Citation Subset:  IM    
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MeSH Terms
Aged, 80 and over
Deglutition Disorders / etiology,  radiography,  therapy*
Dementia / complications*
Middle Aged
Multivariate Analysis
Parkinson Disease / complications*
Pneumonia, Aspiration / prevention & control*
Grant Support
M01 RR003186/RR/NCRR NIH HHS; M01 RR003186-190295/RR/NCRR NIH HHS; U01 DC003206/DC/NIDCD NIH HHS; U01 DC003206-07/DC/NIDCD NIH HHS
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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