Document Detail

A randomized study comparing retroperitoneal drainage with no drainage after lymphadenectomy in gynecologic malignancies.
MedLine Citation:
PMID:  9190979     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To evaluate the clinical effectiveness of retroperitoneal drainage following lymphadenectomy in gynecologic surgery. METHODS: One hundred thirty-seven consecutive patients undergoing systematic lymphadenectomy for gynecologic malignancies were randomized to receive (Group A, 68) or not (Group B, 69) retroperitoneal drainage. The pelvic peritoneum and the paracolic gutters were not sutured after node dissection. Perioperative data and complications were recorded. RESULTS: Clinical and surgical parameters were comparable in the two groups. Postoperative hospital stay was significantly shorter in Group B (P < 0.001), whereas the complication rate was significantly higher in Group A (P = 0.01). This was mainly due to a significant increase in lymphocyst and lymphocyst-related morbidity. Sonographic monitoring for lymphocyst showed free abdominal fluid in 18% of drained and 36% of not-drained patients (P = 0.03). Symptomatic ascites developed in 2 drained (3%) and 3 not-drained (4%) patients (NS), respectively. CONCLUSIONS: Prophylactic drainage of the retroperitoneum seems to increase lymphadenectomy-related morbidity and postoperative stay. Therefore, routine drainage following lymphadenectomy seems to be no longer indicated when the retroperitoneum is left open.
P Benedetti-Panici; F Maneschi; G Cutillo; G D'Andrea; V S di Palumbo; M Conte; G Scambia; S Mancuso
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Gynecologic oncology     Volume:  65     ISSN:  0090-8258     ISO Abbreviation:  Gynecol. Oncol.     Publication Date:  1997 Jun 
Date Detail:
Created Date:  1997-07-14     Completed Date:  1997-07-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0365304     Medline TA:  Gynecol Oncol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  478-82     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Catholic University of the Sacred Heart, Rome, Italy.
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MeSH Terms
Drainage* / methods
Lymph Node Excision* / adverse effects
Middle Aged
Ovarian Neoplasms / surgery*
Postoperative Care*
Postoperative Complications / epidemiology,  prevention & control
Retroperitoneal Space
Uterine Neoplasms / surgery*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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