Document Detail

A randomized prospective trial comparing the levonorgestrel-releasing intrauterine system with thermal balloon ablation for the treatment of heavy menstrual bleeding.
MedLine Citation:
PMID:  20159179     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Use of the levonorgestrel-releasing intrauterine system (LNG-IUS) was compared with thermal balloon ablation (TBA) for the treatment of heavy menstrual bleeding (HMB). STUDY DESIGN: A prospective randomized trial comparing the LNG-IUS (n=30 women) and TBA (n=28 women). RESULTS: Hemoglobin levels increased (p<.001) and blood loss was reduced (p<.001) in both groups after 1 year of treatment. Menstrual bleeding was less in the LNG-IUS group compared to the TBA group at 6 and 12 months of treatment (p=.035 and p=.048, respectively). Intermenstrual bleeding was significantly less in the TBA group at 6 months compared to the LNG-IUS group (p=.044); however, there was no significant difference at 12 months (p=.129). No difference was found in psychological aspects between pre- and posttreatment variables in either of the groups (p=.537). CONCLUSIONS: Both the LNG-IUS and TBA appear to be effective in controlling HMB; however, posttreatment uterine bleeding patterns are different.
S?rgio S de Souza; Aroldo F Camargos; Carolina P de Rezende; Francisco A N Pereira; C?cero A A Ara?jo; Agnaldo L Silva Filho
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Publication Detail:
Type:  Comparative Study; Journal Article; Randomized Controlled Trial     Date:  2009-10-29
Journal Detail:
Title:  Contraception     Volume:  81     ISSN:  1879-0518     ISO Abbreviation:  Contraception     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-02-17     Completed Date:  2010-05-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0234361     Medline TA:  Contraception     Country:  United States    
Other Details:
Languages:  eng     Pagination:  226-31     Citation Subset:  IM    
Copyright Information:
Copyright (c) 2010 Elsevier Inc. All rights reserved.
Professor Aroldo Fernando Camargos Laboratory of Human Reproduction, Teaching Hospital of the Federal University of Minas Gerais, Minas Gerais, Brazil.
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MeSH Terms
Analysis of Variance
Balloon Dilatation / methods
Endometrial Ablation Techniques*
Hemoglobins / analysis
Intrauterine Devices, Medicated*
Levonorgestrel / therapeutic use*
Menorrhagia / therapy*
Patient Satisfaction
Patient Selection
Quality of Life
Treatment Outcome
Reg. No./Substance:
0/Hemoglobins; 797-63-7/Levonorgestrel

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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