Document Detail

A randomized controlled trial of a public health nurse directed treatment program for rural patients with high blood cholesterol.
MedLine Citation:
PMID:  12634025     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Many rural residents do not have access to high-quality nutrition counseling for high blood cholesterol. The objective of this study was to assess the effectiveness of an intervention program designed to facilitate dietary counseling for hypercholesterolemia by rural public health nurses. METHODS: Eight health departments (216 participants) were randomized to give the special intervention (SI) and nine (252 participants) to give the minimal intervention (MI). The SI consisted of three individual diet counseling sessions given by a public health nurse, using a structured dietary intervention (Food for Heart Program), referral to a nutritionist if lipid goals were not achieved at 3-month follow-up, and a reinforcement phone call and newsletters. Diet was assessed by the Dietary Risk Assessment (DRA), a validated food frequency questionnaire, at baseline, 3-, and 12-month follow-up; blood lipids and weight were assessed at baseline, 3-, 6-, and 12-month follow-up. RESULTS: Participants were largely female (71%), older (mean age 55), and white (80%). At 3-month follow-up, the average reduction (indicating dietary improvement) in total Dietary Risk Assessment score was 3.7 units greater in the SI group (95% confidence interval [CI] 1.9 to 5.5, P = 0.0006), while both groups experienced a similar reduction in blood cholesterol, 14.1 mg/dL (0.37 mmol/L) for SI and 14.5 mg/dL (0.38 mmol/L) for minimal intervention group (difference -0.4 mg/dL [-0.010 mmol/L], 95% CI -12.5 to 11.7 [-0.32 to 0.30], P = 0.9). At 12-month follow-up, the reduction in total Dietary Risk Assessment score was 2.1 units greater in the SI group (95% CI 0.8 to 3.5, P = 0.005), while the reduction in blood cholesterol was similar in both groups, 18.4 mg/dL (0.48 mmol/L) for SI and 15.6 mg/dL (0.40 mmol/L) for minimal intervention group (difference 2.8 mg/dL [0.07 mmol/L], 95% CI -7.5 to 13.1 [-0.19 to 0.34], P = 0.6). During follow-up, weight loss was greater in the SI group; the difference between groups was statistically significant at 3 (1.9 lb [0.86 kg], 95% CI 0.3 to 3.4 [0.14 to 1.55], P = 0.022) and 6 months (2.1 lb [0.95 kg], 95% CI 0.1 to 4.1 [0.04 to 1.86], P = 0.04). At 12 months, the difference was not significant (1.6 lb [0.73 kg], 95% CI -0.05 to 3.7 [-0.02 to 1.68], P = 0.13). CONCLUSIONS: Improvement in self-reported dietary intake was significantly greater in the SI group, while reduction in blood cholesterol was similar in both groups.
Alice S Ammerman; Thomas C Keyserling; Jan R Atwood; James D Hosking; Hany Zayed; Cristina Krasny
Related Documents :
8546515 - Response to drugs and diet in a compound heterozygote for familial hypercholesterolaemia.
10080485 - Endothelium-dependent relaxation by acetylcholine is impaired in hypertriglyceridemic h...
11063475 - Efficacy and safety of lowering dietary intake of total fat, saturated fat, and cholest...
12405655 - Exercise- and metabolism-associated blood variables in standardbreds fed either a low- ...
10606215 - Muscle structure with low- and high-fat diets in well-trained male runners.
6317825 - The effect of pectin on the utilization of marginal levels of dietary protein by weanli...
Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Preventive medicine     Volume:  36     ISSN:  0091-7435     ISO Abbreviation:  Prev Med     Publication Date:  2003 Mar 
Date Detail:
Created Date:  2003-03-13     Completed Date:  2003-07-23     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0322116     Medline TA:  Prev Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  340-51     Citation Subset:  IM    
Department of Nutrition, Schools of Public Health and Medicine, University of North Carolina at Chapel Hill, 27599, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Blood Chemical Analysis
Cholesterol, LDL / analysis*
Coronary Disease / prevention & control*
Dietary Fats / adverse effects*
Follow-Up Studies
Hypercholesterolemia / diet therapy*,  nursing*
Intervention Studies
Middle Aged
North Carolina
Nurse-Patient Relations
Nutrition Assessment
Patient Compliance
Preventive Medicine / methods
Public Health Nursing
Reference Values
Risk Assessment
Rural Population
Sampling Studies
Treatment Outcome
Grant Support
Reg. No./Substance:
0/Cholesterol, LDL; 0/Dietary Fats

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Associations of weight loss and changes in fat distribution with the remission of hypertension in a ...
Next Document:  A national survey of primary care physicians' colorectal cancer screening recommendations and practi...