| A randomized controlled trial of the efficacy and cost-effectiveness of a brief intensified cognitive behavioral therapy and/or pharmacotherapy for mood and anxiety disorders: Design and methods. | |
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MedLine Citation:
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PMID: 22588010 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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BACKGROUND: Anxiety and mood disorders involve a high disease burden and are associated with high economic costs. A stepped-care approach intervention and abbreviated diagnostic method are assumed to increase effectiveness and efficiency of the mental healthcare and are expected to reduce economic costs. METHODS: Presented are the rationale, design, and methods of a two-armed randomized controlled trial comparing 'treatment as usual' (TAU) with a brief intensified cognitive behavioral therapy (CBT) and/or pharmacotherapy. Eligible participants (N=500) of five Dutch outpatient Mental Healthcare Centers are randomly assigned to either TAU or to the experimental condition (brief CBT and/or pharmacotherapy). Data on patients' progress and clinical effectiveness of treatment are assessed at baseline, post-treatment (3months after baseline), and at 6 and 12months post-treatment by Routine Outcome Monitoring (ROM). Cost analysis is performed on the obtained data. DISCUSSION: Since few studies have investigated both the clinical and cost effectiveness of a stepped-care approach intervention and a shortened diagnostic ROM method in both anxiety and/or mood disorders within secondary mental health care, the results of this study might contribute to the improvement of (cost)-effective treatment options and diagnostic methods for these disorders. |
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Authors:
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Denise Meuldijk; Ingrid V E Carlier; Irene M van Vliet; M Elske van den Akker-Marle; Frans G Zitman |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-5-12 |
Journal Detail:
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Title: Contemporary clinical trials Volume: - ISSN: 1559-2030 ISO Abbreviation: - Publication Date: 2012 May |
Date Detail:
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Created Date: 2012-5-16 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101242342 Medline TA: Contemp Clin Trials Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2012. Published by Elsevier Inc. |
Affiliation:
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Department of Psychiatry, Leiden University Medical Center, Leiden, the Netherlands. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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