Document Detail


A randomized controlled trial comparing the efficacy and acceptability of phospo-soda buffered saline (Fleet) with sodium picosulphate/magnesium citrate (Picoprep) in the preparation of patients for colonoscopy.
MedLine Citation:
PMID:  17868404     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: Small-volume bowel preparations for colonoscopy has become increasingly popular due to improved tolerance by patients and equivalent efficacy compared with the larger volume preparations. Comparative studies, however, between small volume preparations are lacking. This randomized controlled trial aimed at comparing the efficacy and acceptability of phospo-soda buffered saline (Fleet) with sodium picosulphate/magnesium citrate (Picoprep) in the preparation of patients for colonoscopy. METHOD: A randomized prospective trial designed to compare the efficacy and acceptability of Fleet with Picoprep in patients undergoing colonoscopy. RESULTS: Seventy-three patients undergoing colonoscopy were randomized to receive either Fleet or Picoprep as bowel preparation. Patients were asked to score the acceptability and to comment specifically on adverse events, namely headache, nausea and vomiting. The efficacy of the preparation was also assessed. The results showed no difference in efficacy (P = 0.06, chi(2) test), but there was a significant difference in acceptability (P = 0.01, chi(2) test). and side effects of patients suffering nausea (P = 0.003, chi(2) test), in favour of Picoprep. CONCLUSION: Whilst there was no difference in efficacy, there was a significant difference in acceptability and side effects in favour of Picoprep.
Authors:
A J Renaut; S Raniga; F A Frizelle; R E Perry; L Guilford
Related Documents :
3510704 - A prospective randomized study of sutured versus stapled bowel anastomoses in patients ...
22117984 - The incidence of postoperative nausea and vomiting after thyroidectomy using three anae...
2321134 - Acute mesenteric ischemia: improved results--a retrospective analysis of ninety-two pat...
7656524 - The use of air or co2 as insufflation agents for double contrast barium enema (dcbe): i...
10804094 - Specific sublingual immunotherapy in atopic dermatitis. results of a 6-year follow-up o...
3990974 - Chronic agonist therapy for parkinson's disease: a 5-year study of bromocriptine and pe...
Publication Detail:
Type:  Comparative Study; Journal Article; Randomized Controlled Trial     Date:  2007-09-13
Journal Detail:
Title:  Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland     Volume:  10     ISSN:  1463-1318     ISO Abbreviation:  Colorectal Dis     Publication Date:  2008 Jun 
Date Detail:
Created Date:  2008-05-15     Completed Date:  2008-07-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100883611     Medline TA:  Colorectal Dis     Country:  England    
Other Details:
Languages:  eng     Pagination:  503-5     Citation Subset:  IM    
Affiliation:
The Oxford Clinic, Christchurch, New Zealand.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Cathartics* / adverse effects
Citric Acid* / adverse effects
Colonoscopy*
Humans
Organometallic Compounds* / adverse effects
Patient Acceptance of Health Care*
Phosphates* / adverse effects
Picolines* / adverse effects
Prospective Studies
Treatment Outcome
Chemical
Reg. No./Substance:
0/Cathartics; 0/Organometallic Compounds; 0/Phosphates; 0/Picolines; 0/magnesium citrate; 10040-45-6/picosulfate sodium; 7632-05-5/sodium phosphate; 77-92-9/Citric Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Botulinum toxin vs glyceryltrinitrate for the medical management of chronic anal fissure: a meta-ana...
Next Document:  The diagnostic value of digital rectal examination in primary care for palpable rectal tumour.