Document Detail

A randomized controlled trial of acetyl salicylic acid in the secondary prevention of mortality from myocardial infarction.
MedLine Citation:
PMID:  4593555     Owner:  NLM     Status:  MEDLINE    
The results of a randomized controlled trial of a single daily dose of acetyl salicylic acid (aspirin) in the prevention of reinfarction in 1,239 men who had had a recent myocardial infarct were statistically inconclusive. Nevertheless, they showed a reduction in total mortality of 12% at six months and 25% at twelve months after admission to the trial. Further trials are urgently required to establish whether or not this effect is real.
P C Elwood; A L Cochrane; M L Burr; P M Sweetnam; G Williams; E Welsby; S J Hughes; R Renton
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  British medical journal     Volume:  1     ISSN:  0007-1447     ISO Abbreviation:  Br Med J     Publication Date:  1974 Mar 
Date Detail:
Created Date:  1974-05-17     Completed Date:  1974-05-17     Revised Date:  2010-10-26    
Medline Journal Info:
Nlm Unique ID:  0372673     Medline TA:  Br Med J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  436-40     Citation Subset:  AIM; IM    
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MeSH Terms
Age Factors
Aspirin / administration & dosage,  therapeutic use*
Clinical Trials as Topic
Follow-Up Studies
Middle Aged
Myocardial Infarction / mortality,  prevention & control*
Platelet Adhesiveness / drug effects
Time Factors
Reg. No./Substance:
0/Placebos; 50-78-2/Aspirin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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