| A randomized comparison of the MCRI On-X and CarboMedics Top Hat bileaflet mechanical replacement aortic valves: early postoperative hemodynamic function and clinical events. | |
| | |
MedLine Citation:
|
PMID: 16153925 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: This study compared hemodynamic function and clinical events in consecutive patients randomly assigned to receive a wholly supra-annular replacement valve or a valve with an intra-annular component. METHODS: Fifty-two patients with an average age of 62 years (range 40-74 years) were sized for both a CarboMedics Top Hat valve (CarboMedics Inc, Austin, Tex) and an MCRI On-X valve (Medical Carbon Research Institute, LLC, Austin, Tex) before random assignment to receive either valve type. Echocardiographic and clinical assessments were performed in the immediate postoperative period and at 1 year. RESULTS: The mean effective orifice areas were 1.41 +/- 0.42 cm2 for the Top Hat and 2.17 +/- 0.78 cm2 for the On-X (P < .0001). The mean pressure differences were 12.2 +/- 4.4 mm Hg and 6.9 +/- 3.6 mm Hg, respectively (P < .0001). New York Heart Association functional class was better with the On-X than the Top Hat valves, but there were no differences in clinical events, regression of left ventricular mass, or measures of hemolysis. CONCLUSION: The partially intra-annular MCRI On-X valve was hemodynamically superior to the wholly supra-annular CarboMedics Top Hat valve. However, there were no differences in early clinical outcomes between the two valve types. |
| | |
Authors:
|
J Chambers; J Roxburgh; C Blauth; J O'Riordan; F Hodson; H Rimington |
Related Documents
:
|
18355515 - Long-term results of aortic valve replacement with a small st. jude medical valve in ja... 9054525 - Differential calcification of cusps and aortic wall of failed stented porcine bioprosth... 8019055 - Pathogenesis and prevention of native valve infective endocarditis in elderly dental pa... 725435 - Surgical approaches to abnormalities of the nasal valve. 7420685 - Bromocriptine for an acromegalic patient. improvement in cardiac function and carpal tu... 1548955 - The next 5 years in cardiac pacemakers: a preview. |
Publication Detail:
|
Type: Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: The Journal of thoracic and cardiovascular surgery Volume: 130 ISSN: 0022-5223 ISO Abbreviation: J. Thorac. Cardiovasc. Surg. Publication Date: 2005 Sep |
Date Detail:
|
Created Date: 2005-09-12 Completed Date: 2005-11-03 Revised Date: 2007-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0376343 Medline TA: J Thorac Cardiovasc Surg Country: United States |
Other Details:
|
Languages: eng Pagination: 759-64 Citation Subset: AIM; IM |
Affiliation:
|
Valve Study Group, Guy's and St Thomas Hospitals, London, United Kingdom. jboydchambers@aol.com |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Aged Aortic Valve / surgery* Aortic Valve Insufficiency / physiopathology, surgery Aortic Valve Stenosis / physiopathology, surgery Cholesterol, LDL / blood Echocardiography Female Follow-Up Studies Heart Valve Prosthesis* Heart Valve Prosthesis Implantation* / mortality Hemodynamics Humans Male Middle Aged Postoperative Complications Prosthesis Design |
| Chemical | |
Reg. No./Substance:
|
0/Cholesterol, LDL |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Intraoperative detection of lymph node micrometastasis with flow cytometry in non-small cell lung ca...
Next Document: Mitral valve repair provides improved outcome over replacement in active infective endocarditis.