Document Detail

A randomised, double-blind study on the efficacy of Tołpa Torf Preparation (TTP) in the treatment of recurrent respiratory tract infections.
MedLine Citation:
PMID:  8239913     Owner:  NLM     Status:  MEDLINE    
TTP is a new immunomodulating drug of natural origin, registered in Poland for human use. In the randomised, double blind study to assess the therapeutic efficacy of the Tołpa Torf Preparation (TTP) in the recurrent respiratory tract infectious participated 39 young patients (age 16-22). TTP was administered orally, 5 mg daily for three weeks. During 3 months follow-up period favourable results of treatment were obtained in 14 of 20 TTP treated patients and in 8 of 19 of the placebo patients. The therapeutic effects were seen even after the 6 months follow-up period. The phagocytic activity of granulocytes was significantly stimulated in the TTP--treated patients but not in the placebo-treated patients. The results suggest that TTP is effective drug in the treatment of recurrent respiratory tract infections with undefined infectious etiology. In the period of the treatment as well as during 6 months observation no side effects were noticed.
A Jankowski; B Nienartowicz; B Polańska; A Lewandowicz-Uszyńska
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Archivum immunologiae et therapiae experimentalis     Volume:  41     ISSN:  0004-069X     ISO Abbreviation:  Arch. Immunol. Ther. Exp. (Warsz.)     Publication Date:  1993  
Date Detail:
Created Date:  1993-12-06     Completed Date:  1993-12-06     Revised Date:  2006-04-17    
Medline Journal Info:
Nlm Unique ID:  0114365     Medline TA:  Arch Immunol Ther Exp (Warsz)     Country:  POLAND    
Other Details:
Languages:  eng     Pagination:  95-7     Citation Subset:  IM    
Department of Pediatric Propedeutics, University Medical School, Wrocław, Poland.
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MeSH Terms
Adjuvants, Immunologic / therapeutic use*
Amino Acids / therapeutic use*
Carbohydrates / therapeutic use*
Double-Blind Method
Drug Combinations
Humic Substances / therapeutic use*
Interferon Inducers / therapeutic use*
Respiratory Tract Infections / drug therapy*
Soil / analysis*
Uronic Acids / therapeutic use*
Reg. No./Substance:
0/Adjuvants, Immunologic; 0/Amino Acids; 0/Carbohydrates; 0/Drug Combinations; 0/Humic Substances; 0/Interferon Inducers; 0/Soil; 0/Tolpa; 0/Uronic Acids

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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