Document Detail

A randomised crossover trial of chest physiotherapy in non-cystic fibrosis bronchiectasis.
MedLine Citation:
PMID:  19541717     Owner:  NLM     Status:  MEDLINE    
Regular chest physiotherapy is advocated in non-cystic fibrosis bronchiectasis despite little evidence supporting its routine use. This study aimed to establish the efficacy of regular chest physiotherapy in non-cystic fibrosis bronchiectasis compared with no regular chest physiotherapy. 20 patients not practising regular chest physiotherapy were enrolled in a randomised crossover trial of 3 months of twice daily chest physiotherapy using an oscillatory positive expiratory pressure device compared with 3 months of no chest physiotherapy. The primary end-point was the Leicester Cough Questionnaire (LCQ). Additional outcomes included 24-h sputum volume, forced expiratory volume in 1 s (FEV(1)), forced vital capacity (FVC), forced expiratory flow at 25-75% of FVC (FEF(25-75%)), maximum inspiratory pressure (MIP), maximum expiratory pressure (MEP), exercise capacity, sputum microbiology and St George's Respiratory Questionnaire (SGRQ). The treatment effect was estimated using the differences of the pairs of observations from each patient. There was a significant improvement in all domains and total LCQ score with regular chest physiotherapy (median (interquartile range) total score improvement 1.3 (-0.17-3.25) units; p = 0.002). 24-h sputum volume increased significantly with regular chest physiotherapy (2 (0-6) mL; p = 0.02), as did exercise capacity (40 (15-80) m; p = 0.001) and SGRQ total score (7.77 (-0.99-14.5) unit improvement; p = 0.004). No significant differences were seen in sputum bacteriology, FEV(1), FVC, FEF(25-75%), MIP or MEP. Regular chest physiotherapy in non-cystic fibrosis bronchiectasis has small, but significant benefits.
M P Murray; J L Pentland; A T Hill
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't     Date:  2009-06-18
Journal Detail:
Title:  The European respiratory journal     Volume:  34     ISSN:  1399-3003     ISO Abbreviation:  Eur. Respir. J.     Publication Date:  2009 Nov 
Date Detail:
Created Date:  2009-11-02     Completed Date:  2010-03-16     Revised Date:  2014-03-17    
Medline Journal Info:
Nlm Unique ID:  8803460     Medline TA:  Eur Respir J     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  1086-92     Citation Subset:  IM    
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MeSH Terms
Bronchiectasis / therapy*
Cross-Over Studies
Cystic Fibrosis / diagnosis
Forced Expiratory Volume
Oscillometry / methods
Physical Therapy Modalities*
Pulmonary Medicine
Treatment Outcome
Vital Capacity
Grant Support
CZB/4/451//Chief Scientist Office; ETM/7//Chief Scientist Office
Comment In:
Eur Respir J. 2009 Nov;34(5):1011-2   [PMID:  19880613 ]
Aust J Physiother. 2009;55(4):285   [PMID:  19929774 ]

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